Advances in Saponin Diversity ofPanax ginseng

文献类型： 外文期刊

第一作者： Piao, Xiangmin

作者： Piao, Xiangmin;Zhang, Hao;Wang, Yingping;Piao, Xiangmin;Zhang, Hao;Li, Yali;Pang, Shifeng;Jin, Yinping;Kang, Jong Pyo;Yang, Dong Uk;Yang, Deok Chun

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关键词： ginsenoside; Panax ginseng; chemical structure; tissue spatial distribution

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

ISSN：

年卷期： 2020 年 25 卷 15 期

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收录情况： SCI

摘要： Ginsenosides are the major bioactive constituents ofPanax ginseng, which have pharmacological effects. Although there are several reviews in regards to ginsenosides, new ginsenosides have been detected continually in recent years. This review updates the ginsenoside list fromP. ginsengto 170 by the end of 2019, and aims to highlight the diversity of ginsenosides in multiple dimensions, including chemical structure, tissue spatial distribution, time, and isomeride. Protopanaxadiol, protopanaxatriol and C17 side-chain varied (C17SCV) manners are the major types of ginsenosides, and the constitute of ginsenosides varied significantly among different parts. Only 16 ginsenosides commonly exist in all parts of a ginseng plant. Protopanaxadiol-type ginsenoside is dominant in root, rhizome, leaf, stem, and fruit, whereas malonyl- and C17SCV-type ginsenosides occupy a greater proportion in the flower and flower bud compared with other parts. In respects of isomeride, there are 69 molecular formulas corresponding to 170 ginsenosides, and the median of isomers is 2. This is the first review on diversity of ginsenosides, providing information for reasonable utilization of whole ginseng plant, and the perspective on studying the physiological functions of ginsenoside for the ginseng plant itself is also proposed.

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