Genome Wide Analysis for Growth at Two Growth Stages in A New Fast-Growing Common Carp Strain (Cyprinus carpio L.)

文献类型： 外文期刊

第一作者： Su, Shengyan

作者： Su, Shengyan;Raouf, Bouzoualegh;He, Xinjin;Cai, Nana;Tang, Yongkai;Su, Shengyan;Raouf, Bouzoualegh;He, Xinjin;Cai, Nana;Tang, Yongkai;Su, Shengyan;Raouf, Bouzoualegh;Li, Xinyuan;Yu, Juhua;Li, JianLin;Yu, Fan;Wang, Meiyao;Tang, Yongkai;He, Xinjin

作者机构：

期刊名称：SCIENTIFIC REPORTS （ 影响因子：4.379； 五年影响因子：5.133 ）

ISSN： 2045-2322

年卷期： 2020 年 10 卷 1 期

页码：

收录情况： SCI

摘要： In order to identify candidate genes or loci associated with growth performance of the newly established common carp strain, Xinlong, we conducted a genome-wide association analysis using 2b-RAD technology on 123 individuals. We constructed two sets of libraries associated with growth-related parameters (weight, length, width and depth) measured at two different grow-out stages. Among the 413,059 SNPs identified using SOAP SNP calling, 147,131 were tested for GWAS after quality filtering. Finally, 39 overlapping SNPs, assigned to four genomic locations, were associated with growth traits in two stages. These loci were assigned to functional classes related to immune response, response to stress, neurogenesis, cholesterol metabolism and development, and proliferation and differentiation of cells. By overlapping results of Plink and EMMAX analyses, we identified three genes: TOX, PLK2 and CD163 (both methods P<0.05). Our study results could be used for marker-assisted selection to further improve the growth of the Xinlong strain, and illustrate that largely different sets of genes drive the growth of carp in the early and late grow-out stages.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序