Ultrasound-assisted extraction extracts from Stemona japonica (Blume) Miq. and Cnidium monnieri (L.) Cuss. could be used as potential Rhipicephalus sanguineus control agents

文献类型: 外文期刊

第一作者: Ni, Jun

作者: Ni, Jun;Ren, Qiaoyun;Luo, Jin;Chen, Ze;Xu, Xiaofeng;Guo, Junhui;Tan, Yangchun;Liu, Wenge;Qu, Zhiqiang;Wu, Zegong;Wang, Jinming;Li, Youquan;Guan, Guiquan;Luo, Jianxun;Yin, Hong;Liu, Guangyuan;Yin, Hong

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关键词: Rhipicephalus sanguineus; Stemona japonica (Blume) Miq.; Cnidium monnieri (L.) Cuss.; Extracts

期刊名称:EXPERIMENTAL PARASITOLOGY ( 影响因子:2.011; 五年影响因子:2.132 )

ISSN: 0014-4894

年卷期: 2020 年 217 卷

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收录情况: SCI

摘要: Nicotiana tabacum, Stemona japonica, and Cnidium monnieri are common plants that are widely used for their antiparasitic properties. The purpose of this study was to evaluate the acaricidal activity of extracts from these plants against the brown dog tick, Rhipicephalus sanguineus. A composition analysis of crude extracts by GC-MS was conducted to discover compounds with acaricidal effects. The toxicity of extraction against the engorged nymphs of R. sanguineus was evaluated by an immersion test. The results showed that the crude extracts of S. japonica and C. monnieri in varying ratios, concentrations, and from different extraction methods, had a killing effect on R. sanguineus. Lethality reached 76.67% +/- 0.04410 when using a 1:1 extract of S. japonica:C. monnieri in 75% ethanol with ultrasonic extraction; the crude extract was determined at a concentration of 0.5 g/mL. GC-MS results showed that osthole and 5-hydroxymethylfurfural (5-HMF) are the main components of the extract. These results suggested that ultrasound-assisted extraction (UAE) extracts contained acaricidal components acting against R. sanguineus, which may result in the development of effective extracts of S. japonica and C. monnieri as a source of low-toxicity, plant-based, natural acaricidal drugs.

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