文献类型： 外文期刊
第一作者： Zhang, Xia
作者： Zhang, Xia;Li, Hui;Su, Meicheng;Tan, Dongfei;Wang, Shaolei;Jia, Man;Chen, Gang;Gan, Min;Li, Jingyun;Zhang, Liguo
作者机构：
关键词： indole pyruvate pathway; IL4I1; IAA; IAld; AHR signaling
期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.279； 五年影响因子：5.269 ）
ISSN： 0021-8561
年卷期： 2020 年 68 卷 39 期
页码：
收录情况： SCI
摘要： L-tryptophan (Trp) is widely used in food and feed enforcement to play an important role in biological processes. Various metabolites of Trp perform its potent function. The indole pyruvate pathway is one of the main pathways of Trp metabolism in the gut microbiota, providing numerous indole-derivatives, which can modulate intestinal homeostasis and mucosal immunity by activating the aryl hydrocarbon receptor (AHR) signaling pathway. In this study, we constructed an IL4I1-overexpressed 293T cell line and found that IL4I1 can catalyze Tip to produce indole-3-acetic acid (IAA) and indole-3-carboxaldehyde (IAld). Moreover, both IAA and IAld are accumulated in dendritic cells (DCs) and can stimulate the expression of CYP1A1. Our results demonstrate the existence of the indole pyruvate pathway in host cells with IL4I1 as the key enzyme. The IL4I1-mediated Trp metabolism implies the role of dietary impact on immunity.
分类号：
- 相关文献
作者其他论文 更多>>
-
A ratiometric fluorescent probe for the determination of quinolone antibiotics in milk based on N and S co-doped carbon quantum dots
作者：Wang, Fang;Li, Xiaoyun;Zhang, Yuchen;Li, Hui;Jiang, Shanxue;Li, Dandan;Yao, Zhiliang;Wang, Fang;Li, Xiaoyun;Zhang, Yuchen;Li, Hui;Jiang, Shanxue;Li, Dandan;Yao, Zhiliang;Wang, Fang;Li, Xiaoyun;Zhang, Yuchen;Li, Hui;Jiang, Shanxue;Li, Dandan;Yao, Zhiliang;Han, Jiajun;Gong, Wenwen
关键词：Carbon quantum dot; Ratiometric fluorescence probe; Moxifloxacin; Gatifloxacin; Ofloxacin; Milk
-
Effects of plant source selection and chemi-mechanical treatment on the fiber microstructures and mechanical behaviors of nanocellulose films
作者：Qian, Yangyang;Qian, Yangyang;Wang, Chunyu;Liu, Yijun;Wei, Yuan;Chen, Gang;Shi, Bingfei;Zhang, Jianqiang;Liu, Yijun
关键词：
-
Trace phospholipid and fatty acid differences between dairy and plant-based milk products by 1 H and 31 P NMR spectroscopy combined with multivariate statistical analysis
作者：Wang, Tongtong;Tan, Sijia;Li, Liang;Jiang, Bin;Wang, Dan;Liu, Qingyi;Chen, Gang
关键词：Dairy cream; Butter; Plant-based cream; Margarine; Multivariate statistical analysis
-
SPTS: Single Pixel in Time-Series Triangle Model for Estimating Surface Soil Moisture
作者：Ma, Tian;Leng, Pei;Aliyu Kasim, Abba;Li, Zhao-Liang;Ma, Tian;Gao, Yu-Xin;Guo, Xiaonan;Zhang, Xia;Shang, Guo-Fei;Li, Zhao-Liang
关键词：Land surface temperature (LST); Landsat; single pixel in time series (SPTS); soil moisture
-
No-tillage practice enhances soil total carbon content in a sandy Cyperus esculentus L. field
作者：Wang, Cong;Hu, Yuxiang;Wu, Hui;Wang, Zhirui;Cai, Jiangping;Wang, Zhengwen;Li, Hui;Wang, Cong;Hu, Yuxiang;Wu, Hui;Liu, Heyong;Jiang, Yong;Ren, Wei;Yang, Ning
关键词：No-tillage; Bacterial community composition; Bacterial function prediction; Aeolian sandy soil;
Cyperus esculentus L. -
Sustainable, biodegradable, and recyclable bioplastics derived from renewable carboxymethyl cellulose and waste walnut shell
作者：Qian, Yangyang;Qin, Changpei;Zhang, Jianqiang;Shi, Bingfei;Wei, Yuan;Niu, Jingchao;Kang, Shimin;Wang, Chunyu;Chen, Gang;Qian, Yangyang;Wei, Yuan;Liu, Yijun
关键词：Carboxymethyl cellulose; Waste walnut shell; One-pot casting; Bioplastics; UV-blocking
-
Kynurenine, a derivative of tryptophan, inhibits progesterone biosynthesis in porcine granulosa luteal cells through Aryl hydrocarbon receptor-mediated downregulation of GATA-binding protein 4, 6, and CCAAT/enhancer-binding protein beta†
作者：Liao, Shiying;Deng, Yanfei;Liao, Shiying;Cheng, Jinhua;Zhao, Weimin;Dai, Chaohui;Fu, Yanfeng;Li, Bixia;Li, Hui;Li, Hui
关键词：kynurenine; progesterone; granulosa luteal cell; STAR; AHR
