Review of the Presence and Phage-Mediated Transfer of ARGs in Biofilms

文献类型： 外文期刊

第一作者： Lu, Han

作者： Lu, Han;Wang, Yanjun;Liu, Hongyuan;Wang, Nana;Zhang, Yan;Li, Xinhua;Lu, Han;Wang, Yanjun;Liu, Hongyuan;Wang, Nana;Zhang, Yan;Li, Xinhua;Lu, Han

作者机构：

关键词： antibiotic resistance genes; biofilm; phage-mediated transfer; resistance gene transfer

期刊名称：MICROORGANISMS （ 影响因子：4.2； 五年影响因子：4.6 ）

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年卷期： 2025 年 13 卷 5 期

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收录情况： SCI

摘要： The widespread use of antibiotics has led to the emergence of a large number of drug-resistant bacteria, accelerating the dissemination and spread of antibiotic resistance genes (ARGs) in the environment. Bacterial biofilms, serving as reservoirs of ARGs, pose potential risks to environmental health that should not be ignored. Studies on the presence and transfer of ARGs in biofilms have been conducted both domestically and internationally. This article summarises the research progress on ARGs in various environments and analyses the mechanisms and factors influencing the dissemination and transfer of ARGs in microplastics, activated sludge, and pipe wall biofilms, with a particular focus on phage-mediated ARG transfer. We also discuss current research gaps in this field to provide references for future biofilm management and health risk control of ARGs.

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