Molecular cloning and characterization of cat, gpx1 and Cu/Zn-sod genes in pengze crucian carp (Carassius auratus var. Pengze) and antioxidant enzyme modulation induced by hexavalent chromium in juveniles
文献类型: 外文期刊
第一作者: Li, Meng
作者: Li, Meng;Zheng, Yao;Zou, Linhu;Sun, Jiejie;Zhang, Yingying;Qin, Fang;Liu, Shaozhen;Wang, Zaizhao;Liang, Hongwei
作者机构:
关键词: Antioxidant enzymes;Biomarkers;Gene expression;Hexavalent chromium;Oxidative stress;Pengze crucian carp
期刊名称:COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY ( 影响因子:3.228; 五年影响因子:3.289 )
ISSN: 1532-0456
年卷期: 2013 年 157 卷 3 期
页码:
收录情况: SCI
摘要: Hexavalent chromium (Cr6+) is a common pollutant transient metal with high toxicity in the environment. The toxicological effects partly result from oxidative damage due to the production of excessive reactive oxygen species (ROS) in the reductive process of Cr6+. To explore the influence of ROS induced directly by Cr6+ on the oxidative stress generation and antioxidant system, the full length cDNAs of antioxidant-related genes cat, gpx1 and Cu/Zn-sod were successfully acquired from pengze crucian carp first and analyzed. Furthermore, the mRNA expression of the antioxidant genes encompassing catalase (cat), copper/zinc superoxide dismutase (Cu/Zn-sod) and glutathione peroxidase (gpx1), antioxidant enzyme activities of CAT, SOD, and GPx and total protein content were further studied in the gill, intestine and liver of pengze crucian carp (Carassius auratus var. Pengze) juveniles upon acute exposure to Cr6+ at concentrations of 0.1, 1.0, 10 and 100 mg/L for 4 days. Differential significant changes of the antioxidant enzymes and gene expression were observed in different tissues. The findings contribute to better understanding the antioxidant mechanisms induced by Cr6+ and selecting the organic-specific sensitive biomarkers to monitor the safety of the aquatic ecosystem. (C) 2013 Elsevier Inc. All rights reserved.
分类号:
- 相关文献
作者其他论文 更多>>
-
The impact of tea polyphenols on the oxidative stability in Antarctic krill meal during storage: phenomena, substances, and potential mechanism
作者:Yang, Liu;Zhang, Shuaishuai;Wang, Xin;Yang, Liu;Zheng, Yao;Zhang, Quantong;Zhang, Shuaishuai;Guo, Quanyou;Zhang, Quantong
关键词:Tea polyphenols; Addition methods; Lipid oxidation; Molecular docking; Antarctic krill (Euphausia superba)
-
Apoptosis, MAPK signaling pathway affected in tilapia liver following nano-microplastics and sulfamethoxazole acute co-exposure
作者:Zheng, Yao;Li, Jiajia;Gao, Jiancao;Hu, Jiawen;Sun, Yi;Zhu, Haojun;Xu, Gangchun;Zheng, Yao;Jin, Wei;Xu, Gangchun
关键词:Liver; Endoplasmic reticulum; MAPK signaling pathway; Acute exposure
-
Muti-Biomarker Approach and IBR Index to Evaluate the Oxidative Stress of Nanoplastic on the Clams, Meretrix meretrix and Sinonovacula constricta
作者:Lv, Linlan;Feng, Wanjun;Sun, Ke;Zhao, Weihong;Jiang, Fengjuan;Yang, Yue;Zhang, Yingying;Sui, Yanming;Dong, Xuexing;Mohamed, Mohsen;Mohamed, Mohsen;Li, Lei
关键词:biomarker; antioxidant enzyme;
Meretrix meretrix ;Sinonovacula constricta ; nanoplastics; oxidative stress -
Muscle Characteristics Comparison Analysis Reveal Differences in the Meat Quality and Nutritional Components of Three Shanghai Local Pig Breeds
作者:Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Jiang, Wei;He, Chuan;Bai, Lan;Wu, Xiao
关键词:local pig breeds; meat quality traits; amino acids; texture; flavored nucleotide
-
Comparison of in vitro digestive characteristics of proteins from different sources in simulated elderly gastrointestinal conditions
作者:Qiu, Zehui;Shi, Yuyao;Shi, Wenzheng;Zhang, Long;Yin, Mingyu;Wang, Xichang;Qiu, Zehui;Shi, Yuyao;Wang, Xichang;Zheng, Yao
关键词:Protein digestibility; In vitro digestion; Elderly; Food sources; Protein composition; Protein structure
-
Investigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis
作者:Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Li, Xin;Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong
关键词:Meishan pig; asthma; transcriptome; metabolome
-
Flavor characterization of pork cuts in Chalu black pigs using multi-omics analysis
作者:Zhang, Yingying;Diao, Yuduan;Huang, Ji;Wang, Hongyang;Tu, Weilong;Zhang, Jiajie;Zhou, Jieke;Tan, Yongsong;Zhang, Yingying;Diao, Yuduan;Huang, Ji;Wang, Hongyang;Tu, Weilong;Zhou, Jieke;Tan, Yongsong;Raza, Sayed Haidar Abbas;Zhang, Jiajie
关键词:Pork; Meat flavor; Muscle fiber type; Chinese indigenous pig; Multi-omics; Chalu black pigs