Whole-genome resequencing of native and imported dairy goat identifies genes associated with productivity and immunity

文献类型： 外文期刊

第一作者： Zhao, Jianqing

作者： Zhao, Jianqing;Mu, Yuanpan;Liu, Baolong;Zhang, Fuhong;Zhu, Lu;Shi, Chenbo;Luo, Jun;Gong, Ping;Lv, Xuefeng

作者机构：

关键词： dairy goat; whole-genome sequence; genetic diversity; selective signal; production traits

期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：2.6； 五年影响因子：3.1 ）

ISSN：

年卷期： 2024 年 11 卷

页码：

收录情况： SCI

摘要： Understanding the differences in genetic variation between local Chinese dairy goat breeds and imported breeds can help germplasm innovation and molecular breeding. However, the research is limited in this area. In this study, whole-genome resequencing data from 134 individuals of both local and imported dairy goat breeds were analyzed, and their differences in genomic genetic variation, genetic diversity, and population structure were subsequently identified. We also screened candidate genes associated with important traits of dairy goats such as milk production (STK3, GHR, PRELID3B), reproduction (ATP5E), growth and development (CTSZ, GHR), and immune function (CTSZ, NELFCD). Furthermore, we examined allele frequency distributions for the genes of interest and found significant differences between the two populations. This study provides valuable resources for the study of genetic diversity in dairy goats and lays the foundation for the selective breeding of dairy goats in the future.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序