文献类型： 外文期刊
第一作者： Zhang, Dajun
作者： Zhang, Dajun;Huang, Qi;Zhao, Dengshuai;Wang, Tianyu;Yu, Dixi;Qin, Limei;Zhang, Keshan;Yang, Jinke
作者机构：
关键词： HAX1; Regulator; Apoptosis; Molecular function; Disease progress
期刊名称：VIRUS GENES （ 影响因子：1.9； 五年影响因子：1.8 ）
ISSN： 0920-8569
年卷期： 2024 年
页码：
收录情况： SCI
摘要： HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell regulatory protein that is widely expressed in cells and has a close relationship with multiple cellular proteins. HAX1 plays important roles in various processes, including the regulation of apoptosis, maintenance of mitochondrial membrane potential stability and calcium homeostasis, occurrence and development of diseases, post-transcriptional regulation of gene expression, and host immune response after viral infection. In this article, we have reviewed the research progress on the biological functions of HAX1, thereby laying a theoretical foundation for further exploration of its underlying mechanisms and targeted application.
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