Polymorphisms within CEBPA, PRKAG3 and SREBF1 Genes Associated with Fat Deposition in Fat-tail Altay Sheep

文献类型： 外文期刊

第一作者： Xiang, Guangming

作者： Xiang, Guangming;Di, Ran;Wang, Yaowu;Wang, Xiangyu;Hu, Wenping;Liu, Qiuyue;Chu, Mingxing;Gan, Shangquan;Liu, Shouren

作者机构：

关键词： Altay sheep; Fat tail; CEBPA; PRKAG3; SREBF1; SNP

期刊名称：PAKISTAN JOURNAL OF ZOOLOGY （ 影响因子：0.687； 五年影响因子：0.736 ）

ISSN： 0030-9923

年卷期： 2022 年 54 卷 2 期

页码：

收录情况： SCI

摘要： The fat tail/rump is considered as an adaptive selection under harsh challenges which serves as a fat store for the animal. However, the mechanism of fat deposition in tail is unclear. The polymorphisms of candidate sheep CEBPA, PRKAG3 and SREBF1 genes and their relationship with fat deposition between fat-tailed (rumped) and thin-tailed breeds were investigated. Two and one SNPs were identified for PRKAG3 and SREBF1 respectively. Genotyping method was used to analyze genotypes among Altay sheep (fat-rumped breed) and White Suffolk (thin-tailed breed) by Sequenom MassArray. For PRKAG3 gene, a c.1744C T SNP and a c.1840C>T SNP have been genotyped. For SREBF1 gene, an unknown synonymous c.2878A>G SNP was detected. The genotype distributions in those two loci were significantly different between fat tail and thin tail breeds by chi-square test (P<0.05).

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[1]Polymorphisms within CEBPA, PRKAG3 and SREBF1 Genes Associated with Fat Deposition in Fat-tail Altay Sheep. Xiang, Guangming,Di, Ran,Wang, Yaowu,Wang, Xiangyu,Hu, Wenping,Liu, Qiuyue,Chu, Mingxing,Gan, Shangquan,Liu, Shouren. 2022

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