文献类型： 外文期刊
第一作者： Han, Hui
作者： Han, Hui;Yi, Bao;Zhong, Ruqing;Wang, Mengyu;Zhang, Shunfen;Chen, Liang;Zhang, Hongfu;Han, Hui;Ma, Jie;Yin, Yulong;Yin, Jie;Zhang, Hongfu;Yin, Yulong
作者机构：
关键词： Gut microbiota; Appetite; Metabolites; Hormone; Immune
期刊名称：MICROBIOME （ 影响因子：14.652； 五年影响因子：15.679 ）
ISSN： 2049-2618
年卷期： 2021 年 9 卷 1 期
页码：
收录情况： SCI
摘要： Feelings of hunger and satiety are the key determinants for maintaining the life of humans and animals. Disturbed appetite control may disrupt the metabolic health of the host and cause various metabolic disorders. A variety of factors have been implicated in appetite control, including gut microbiota, which develop the intricate interactions to manipulate the metabolic requirements and hedonic feelings. Gut microbial metabolites and components act as appetite-related signaling molecules to regulate appetite-related hormone secretion and the immune system, or act directly on hypothalamic neurons. Herein, we summarize the effects of gut microbiota on host appetite and consider the potential molecular mechanisms. Furthermore, we propose that the manipulation of gut microbiota represents a clinical therapeutic potential for lessening the development and consequence of appetite-related disorders.
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