Antitumor Peptides from Marine Organisms

文献类型: 外文期刊

第一作者: Lin, Xiu-Kun

作者: Lin, Xiu-Kun;Lin, Xiu-Kun;Zheng, Lan-Hong;Wang, Yue-Jun;Sheng, Jun;Wang, Fang;Zheng, Yuan;Sun, Mi

作者机构:

关键词: antitumor;peptides;marine organisms

期刊名称:MARINE DRUGS ( 影响因子:5.118; 五年影响因子:5.951 )

ISSN: 1660-3397

年卷期: 2011 年 9 卷 10 期

页码:

收录情况: SCI

摘要: The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.

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