Immunomagnetic separation for the enrichment of trace enrofloxacin and analysis of degradation byproducts in water

文献类型： 外文期刊

第一作者： Yang, Ruonan

作者： Yang, Ruonan;Li, Bingzhi;Song, Chao;Zhu, Lei;Gao, Yuxiao;Meng, Shunlong;Song, Chao;Fang, Longxiang;Meng, Shunlong;Song, Chao;Fang, Longxiang;Meng, Shunlong;Song, Chao;Fang, Longxiang;Meng, Shunlong;Song, Chao;Fang, Longxiang;Meng, Shunlong;Song, Chao

作者机构：

关键词： degradation mechanisms; enrofloxacin; immunomagnetic separation; toxicity assessment; trace antibiotics

期刊名称：WATER REUSE （ 影响因子：3.3； 五年影响因子：3.6 ）

ISSN： 2709-6092

年卷期： 2024 年 14 卷 4 期

页码：

收录情况： SCI

摘要： The presence of trace antibiotics in water can lead to the development of drug-resistant bacterial strains, posing risks to ecosystems and human health. Immunomagnetic separation (IMS) using magnetic nanoparticles (MNPs) is an effective technique for targeted enrichment. This study established and optimized a separation system for the immunomagnetic microsphere enrichment of enrofloxacin (ENR) antibiotics, achieving efficient enrichment and isolation of ENR. To address potential elution degradation, an analysis of ENR degradation pathways and toxicity assessment of degradation products was performed. The study manifested the successful conjugation of antibodies to magnetic microspheres, leading to a 97.68% separation efficiency for ENR in water through IMS. Specifically, 1 mg of MNP@Ab could specifically bind to 1.5 ng of ENR at 37 degrees C for 30 min, and the elution rate exceeded 83%. No degradation products of ENR were detected during the enrichment and isolation procedures. Nevertheless, extending the elution time to 1 h disclosed three major degradation pathways with higher toxicity risks than ENR based on ecological risk assessment. To strictly control the elution temperature and elution time, the increase in temperature and time will heighten the risk of degradation products. This study presents an efficient strategy for water treatment and environmental protection.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序