Metabolomics profiles and health-promoting functions of tea chrysanthemum using comparative analysis and network pharmacology

文献类型： 外文期刊

第一作者： Fu, Manman

作者： Fu, Manman;Guo, Fangqi;Wu, Chao;Liu, Chen;Chen, Jialong

作者机构：

关键词： Tea chrysanthemum; Widely targeted metabolomics; Pharmacological ingredients; Multi-target pharmacology; Flavones

期刊名称：FOOD BIOSCIENCE （ 影响因子：5.9； 五年影响因子：6.1 ）

ISSN： 2212-4292

年卷期： 2025 年 72 卷

页码：

收录情况： SCI

摘要： Chrysanthemum has a long history of being consumed as tea and possesses health-promoting properties, but the diversity of its related metabolites remains largely unexplored. To identify the metabolites and compare differences among four tea chrysanthemum varieties, a widely targeted metabolome analysis was conducted. In total, we identified 2188 metabolites, of which 40 metabolites were identified as potential crucial active ingredients in Traditional Chinese Medicines. Network pharmacology analysis indicated that 25 active pharmaceutical ingredients found might be related to cardiovascular disease, epilepsy, neurodevelopmental disorder, and Alzheimer disease. Comparative metabolome analysis manifested different metabolomic profiles between Ziju (ZJ) and other three chrysanthemum varieties. The shared differential metabolites from comparisons of ZJ with Hangbaiju, Wuyuanhuangju, and Jinsihuangju were mainly enriched in flavones aglycones III, luteolin aglycones, and flavones aglycones II biosynthesis pathways. Our research enhances the understanding of metabolites composition and active ingredients in tea chrysanthemum, thereby providing valuable insights for the development of the tea chrysanthemum industry.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序