Adsorption and desorption behaviors on microporous resins of antioxidant and anti-proliferation polyphenols from European plum
文献类型： 外文期刊
第一作者： Li, Wenfeng
作者： Li, Wenfeng;Fu, Xueqin;Tang, Jingran;Yan, Shengkun;Yang, Hongyan
作者机构：
关键词： Purification; Antioxidant; Anti-proliferation; Neochlorogenic acid; European plum
期刊名称：FOOD RESEARCH INTERNATIONAL （ 影响因子：8.0； 五年影响因子：8.5 ）
ISSN： 0963-9969
年卷期： 2025 年 199 卷
页码：
收录情况： SCI
摘要： Six macroporous resins (MRs) were employed for the adsorption and desorption of neochlorogenic acid-enriched polyphenols from the European plum (NAPEP). X-5 exhibited the most significant neochlorogenic acid adsorption (99.62 %), desorption (44.80 %), and recovery (44.29 %) rates. The adsorption kinetics were described using a pseudo-second-order model while the Freundlich model indicated that X-5-adsorbing NAPEP was a spontaneous, exothermic process. NAPEP was effectively eluted from X-5 using a 60 % ethanol solution. Ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry (UHPLC-QqQ-MS/MS) revealed the presence of 21 polyphenol compounds in NAPEP, with chlorogenic acids accounting for 93 % of the overall composition. NAPEP demonstrated antioxidant efficacy comparable to chlorogenic acid. Furthermore, NAPEP administration effectively triggered apoptosis in A549 cells by producing reactive oxygen species, which regulated the AKT pathway. These results indicated that NAPEP could be utilized as an antioxidant and anticancer agent in functional foods.
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