Toxic threshold of dietary microcystin (-LR) for quart medaka

文献类型： 外文期刊

第一作者： Deng, Dong-Fang

作者： Deng, Dong-Fang;Teh, Foo-Ching;Teh, Swee J.;Deng, Dong-Fang;Teh, Foo-Ching;Teh, Swee J.;Zheng, Keke;Lehman, Peggy W.

作者机构：

关键词： Apoptosis;Microcystin;Medaka;Protein phosphatase;Reproduction;Stress protein

期刊名称：TOXICON （ 影响因子：3.033； 五年影响因子：2.689 ）

ISSN： 0041-0101

年卷期： 2010 年 55 卷 4 期

页码：

收录情况： SCI

摘要： This study was designed to estimate the toxic threshold of male and female fish to microcystins based on different biomarkers. Japanese medaka (Oryzias latipes) were fed dietary Microcystin-LR (0, 0.46, 0.85, 2.01 and 3.93 mu g MC-LR/g dry diet for 8 weeks at 25 degrees C. The results revealed that dietary MC-LR inhibited growth at the end of 8 weeks. The survival of embryos and the RNA/DNA ratio of whole fish decreased significantly (P < 0.05) in fish fed 3.93 mu g MC-LR/g dry diet. Heat shock protein (Hsp60) expression was induced in the liver of female and male fish fed diets containing >= 0.85 and 0.46 mu g MC-LR/g diet, respectively. The activity of liver caspase 3/7 was significantly higher in female fish fed 3.93 mu g MC-LR/g diet and in males fed 2.01 MC-LR mu g/g dry diet than fish fed the control diet. The threshold for inhibition of liver protein phosphatase expression was lower in female (2.01 mu g/g diet) than that in male fish (3.93 mu g/g diet). Histopathological examination showed significant single-cell necrosis in female and male medaka fed diets containing 0.85 and 3.93 mu g MC-LR/g diet, respectively. Based on different biomarkers, this study demonstrated that dietary MC-LR is toxic to Medaka and the effects are gender dependent. Published by Elsevier Ltd.

分类号：

  • 相关文献

[1]A wheat (Triticum aestivum) protein phosphatase 2A catalytic subunit gene provides enhanced drought tolerance in tobacco. Xu, Chongyi,Jing, Ruilian,Mao, Xinguo,Jia, Xiaoyun,Chang, Xiaoping.

[2]Sperm nuclear transfer and transgenic production in the fish medaka. Liu, Tongming,Hong, Yunhan,Liu, Ling,Wei, Qiwei,Hong, Yunhan.

[3]Medaka tert produces multiple variants with differential expression during differentiation in vitro and in vivo. Rao, Feng,Wang, Tiansu,Li, Mingyou,Li, Zhendong,Hong, Ni,Zhao, Haobin,Yan, Yan,Lu, Wenqing,Chen, Tiansheng,Wang, Weijia,Lim, Menghuat,Yuan, Yongming,Hong, Yunhan,Yan, Yan,Li, Changming,Zhao, Haobin,Liu, Ling,Zeng, Lingbing,Wei, Qiwei,Hong, Yunhan,Guan, Guijun.

[4]Isolation of a Arthrobacter sp T11 that Degrades Cyanobacterial Hepatotoxin Microcystin from the Sediment of a Shallow Hypertrophic Lake. Qu, Jiangqi,Zhang, Qingjing,Zhang, Mo,Xin, Zhiming,Li, Hongwei,Zhang, Nan. 2015

[5]Bioaccumulation of microcystin and its oxidative stress in the apple (Malus pumila). Chen, Jianzhong,Zhang, Haiyang,Wang, Chenyi,Zhou, Guoqing,Han, Zhiping,Chen, Jianzhong,Liu, Zhili,Dai, Jian. 2010

[6]Effects of inorganic arsenic on growth and microcystin production of a Microcystis strain isolated from an algal bloom in Dianchi Lake, China. Ao HongYi,Song LiRong,Liu JianTong,Gong Yan,Hu DingJing,Zhang XingZhong,Liu BiBo,Wen Sheng,Wang Zhi. 2011

[7]Analysis of trace microcystins in vegetables using matrix solid-phase dispersion followed by high performance liquid chromatography triple quadrupole mass spectrometry detection. Qian, Zong-Yao,Li, Zhi-Gang,Ma, Jian,Gong, Ting-Ting,Xian, Qi-Ming,Qian, Zong-Yao.

[8]Optimization and evaluation of microencapsulated artificial diet for mass rearing the predatory ladybird Propylea japonica (Coleoptera: Coccinellidae). Tan, Xiao-Ling,Wang, Su,Zhang, Fan,Tan, Xiao-Ling,Zhao, Jing. 2015

[9]Polymorphism in NPY and IGF-I genes associate with reproductive traits in Wenchang chicken. Li, H. F.,Zhu, W. Q.,Chen, K. W.,Tang, Q. P.,Gao, Y. S.,Song, W. T.,Xu, H. L.,Wu, X.,Xu, H. L.. 2009

[10]The distribution, establishment and life-history traits of non-native sailfin catfishes Pterygoplichthys spp. in the Guangdong Province of China. Wei, Hui,Liu, Fei,Gu, Dangen,Luo, Du,Xu, Meng,Mu, Xidong,Hu, Yinchang,Copp, Gordon H.,Copp, Gordon H.,Copp, Gordon H.,Vilizzi, Lorenzo,Liu, Fei. 2017

[11]Relationship of flight and reproduction in beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae), a migrant lacking the oogenesis-flight syndrome. Jiang, Xing Fu,Luo, Li Zhi,Sappington, Thomas W.. 2010

[12]Identification and comparative profiling of ovarian and testicular microRNAs in the swimming crab Portunus trituberculatus. Liu, Ping. 2018

[13]REPRODUCTIVE BIOLOGY AND GROWTH OF THE DEEP-WATER SHRIMP SOLENOCERA MELANTHO IN THE EAST CHINA SEA. Li, Hui Yu,Cheng, Jia Hua,Li, Sheng Fa. 2012

[14]Association of CYP19A1 gene polymorphisms with reproductive traits in pigs. Zhou Rong,Chen Jie,Li Kui,Zhou Rong,Yang Ya-lan,Liu Ying,Li Kui,Chen Qi-mei. 2017

[15]Molecular characterization and quantification of estrogen receptors in turbot (Scophthalmus maximus). Hu, Peng,Meng, Zhen,Jia, Yudong. 2018

[16]Biochemical composition and quality of turbot (Scophthalmus maximus) eggs throughout the reproductive season. Jia, Yudong,Meng, Zhen,Liu, Xinfu,Lei, Jilin,Jia, Yudong,Meng, Zhen,Liu, Xinfu,Lei, Jilin. 2014

[17]SEASONAL VARIATIONS OF WATER TEMPERATURE, FOOD AVAILABILITY, SIZE, AND REPRODUCTION ON THE HEMOCYTE PARAMETERS IN THE SCALLOP CHLAMYS FARRERI. Lin, Tingting,Li, Ziniu,Xing, Jing,Lin, Tingting,Zhou, Kai,Lai, Qifang,Yao, Zongli,Li, Ziniu. 2012

[18]FEEDING ON A BEGOMOVIRUS-INFECTED PLANT ENHANCES FECUNDITY VIA INCREASED EXPRESSION OF AN INSULIN-LIKE PEPTIDE IN THE WHITEFLY, MEAM1. Cheng, Lu,Ye, Gong-Yin,Fang, Qi,Guo, Jian-Yang.

[19]Effects of daidzein on egg production and gonadotropin related gene expression in the ovary and follicles of laying hens. Shen, Yiru,Wang, Qiang,Shao, Dan,Zhao, Xu,Hu, Yan,Tong, H. B.,Shi, S. R.,Shi, S. R..

[20]Effects of mating rates on oviposition, sex ratio and longevity in a predatory mite Neoseiulus cucumeris (Acari : Phytoseiidae). Ji, Jie,Zhang, Zhi-Qiang,Zhang, YanXuan,Chen, Xia,Lin, JianZhen. 2007

作者其他论文 更多>>

微信小程序