Differences of gut microbiota composition in mice supplied with polysaccharides from gamma-irradiated and non-irradiated Schizophyllum commune
文献类型： 外文期刊
第一作者： Yin, Chaomin
作者： Yin, Chaomin;Fan, Xiuzhi;Chen, Zheya;Yao, Fen;Shi, Defang;Li, Yuhong;Gao, Hong;Qiao, Xin;Gao, Hong
作者机构：
关键词： Polysaccharides; Gut microbiota; Short-chain fatty acids; Fecal microbiota diversity
期刊名称：FOOD RESEARCH INTERNATIONAL （ 影响因子：7.425； 五年影响因子：7.716 ）
ISSN： 0963-9969
年卷期： 2022 年 151 卷
页码：
收录情况： SCI
摘要： In this study, polysaccharides from normal (N-SFP) and gamma-irradiated (I-SFP) Schizophyllum commune were supplied to Kunming mice for 30 days. The results showed that N-SFP and I-SFP supplementation prevent body weight gain, enhance kidney uric acid metabolism and increase the concentration of SCFAs to a certain extent. Moreover, N-SFP and I-SFP promote the growth of beneficial gut microbiota and inhibit the growth of harmful bacteria. Compared to N-SFP, I-SFP decreased the relative abundance of Muribaculaceae and Lactobacillaceae , and increased the beneficial gut microbiota, especially the family of Akkermansiaceae , Lachnospiraceae and Bacteroidaceae. In total, I-SFP showed better effects than N-SFP in preventing weight gain, and modulating the mice gut microbiota, which suggests that I-SFP could act as a potential health supplement in the prevention of obesity.
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