Generation of an infectious cDNA clone for NADC30-like PRRSV

文献类型： 外文期刊

第一作者： Qiao, Yang-Yang

作者： Qiao, Yang-Yang;Wang, Hai-Ming;Lu, Hui;Wang, Yong-Juan;Zhang, Wei;Gu, Hao;Xu, Qin-Se;Chen, Zhang-Yan;Cai, Xue-Hui;Tang, Yan-Dong;Tang, Yan-Dong

作者机构：

关键词： NADC30-like; infectious cDNA clone; PRRSV; NADC30; PRRSV-2

期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：2.9； 五年影响因子：3.3 ）

ISSN：

年卷期： 2024 年 11 卷

页码：

收录情况： SCI

摘要： The porcine reproductive and respiratory syndrome virus (PRRSV) is a highly significant infectious disease that poses a substantial threat to the global pig industry. In recent years, the NADC30-like strain has gradually emerged as prevalent in China, causing a profound impact on the country's pig farming industry. Therefore, it is important to conduct an in-depth study on the characteristics and gene functions of the NADC30-like strain. An infectious cDNA clone is an indispensable tool for investigating the functions of viral genes. In this current study, we successfully isolated a NADC30-like strain and constructed its full-length infectious cDNA clone. The utilization of this clone will facilitate our investigation into the viral replication, pathogenesis, and immune response associated with the PRRSV NADC30-like strain.

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