Application of hair analysis in the monitoring of abuse of β-agonists: A review

文献类型: 外文期刊

第一作者: Suo, Decheng

作者: Suo, Decheng;Fan, Xia;Su, Xiaoou;Wang, Peilong;Wang, Ruiguo;Li, Yang;Zhang, Wei;Xiao, Zhimin

作者机构:

关键词: agonists; Hair; Sample preparation; Analytical techniques; Purification

期刊名称:JOURNAL OF CHROMATOGRAPHY A ( 影响因子:4.0; 五年影响因子:3.6 )

ISSN: 0021-9673

年卷期: 2025 年 1748 卷

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收录情况: SCI

摘要: beta-agonists are prohibited substances for athletes according to the World Anti-Doping Agency and are banned as growth promoters for livestock in most countries. The illicit use of beta-agonists is a significant concern for both human and animal health. Hair analysis serves as a valuable material for monitoring the abuse of beta-agonists. This manuscript aims to provide a comprehensive overview of the application of hair analysis in monitoring beta-agonist abuse. The morphology, structures, and composition of hair are summarized, along with an introduction to the mechanisms of beta-agonist incorporation into hair. Considering various factors, the treatment procedures for beta-agonist detection in hair, with special attention to the authentic matrix, are outlined. Additionally, diverse screening and confirmatory methods are reviewed. Particular emphasis is placed on novel purification processes and innovative analytical technologies employed for the analysis of beta-agonists in hair.

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