Genome-wide association study and its applications in the non-model crop Sesamum indicum

文献类型: 外文期刊

第一作者: Berhe, Muez

作者: Berhe, Muez;Dossa, Komivi;You, Jun;Zhang, Xiurong;Wang, Linhai;Berhe, Muez;Dossa, Komivi;Diallo, Idrissa Navel;Diouf, Diaga;Dossa, Komivi;Mboup, Pape Adama;Diallo, Idrissa Navel

作者机构:

关键词: GWAS; Sesame; Statistical models; Genomics assisted breeding

期刊名称:BMC PLANT BIOLOGY ( 影响因子:4.215; 五年影响因子:4.96 )

ISSN: 1471-2229

年卷期: 2021 年 21 卷 1 期

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收录情况: SCI

摘要: Background: Sesame is a rare example of non-model and minor crop for which numerous genetic loci and candidate genes underlying features of interest have been disclosed at relatively high resolution. These progresses have been achieved thanks to the applications of the genome-wide association study (GWAS) approach. GWAS has benefited from the availability of high-quality genomes, re-sequencing data from thousands of genotypes, extensive transcriptome sequencing, development of haplotype map and web-based functional databases in sesame. Results: In this paper, we reviewed the GWAS methods, the underlying statistical models and the applications for genetic discovery of important traits in sesame. A novel online database SiGeDiD (http://sigedid.ucad.sn/) has been developed to provide access to all genetic and genomic discoveries through GWAS in sesame. We also tested for the first time, applications of various new GWAS multi-locus models in sesame. Conclusions: Collectively, this work portrays steps and provides guidelines for efficient GWAS implementation in sesame, a non-model crop.

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