文献类型： 外文期刊
第一作者： Wang, Mengyao
作者： Wang, Mengyao;Han, Hongbing;Wang, Mengyao;Han, Hongbing;Wang, Mengyao;Han, Hongbing;Fan, Ziyao
作者机构：
关键词： Staphylococcus aureus; autophagy; accessory gene regulatory system; intracellular persistence; host-pathogen interactions
期刊名称：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY （ 影响因子：5.293； 五年影响因子：5.882 ）
ISSN： 2235-2988
年卷期： 2021 年 11 卷
页码：
收录情况： SCI
摘要： Staphylococcus aureus is an invasive, facultative intracellular pathogen that can colonize niches in various host organisms, making it difficult for the host immune system to completely eliminate. Host autophagy is an intracellular clearance pathway involved in degrading S. aureus. Whereas the accessory gene regulatory system of S. aureus that controls virulence factors could resist the host immune defenses by evading and even utilizing autophagy. This article reviews the interaction between autophagy and S. aureus, providing insights on how to use these mechanisms to improve S. aureus infection control.
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