Study of Synthesis and Biological Activities of a Novel Macrolide Derivatives

文献类型： 外文期刊

第一作者： Shi Daxin

作者： Shi Daxin;Feng Xue;Zhuang Xiaolei;Chai Hongxin;Zhang Qi;Li Jiarong;Liu Ting

作者机构：

关键词： macrolide;acylate;insecticidal activity;fungicidal activity

期刊名称：CHINESE JOURNAL OF ORGANIC CHEMISTRY （ 影响因子：1.652； 五年影响因子：1.2 ）

ISSN： 0253-2786

年卷期： 2014 年 34 卷 12 期

页码：

收录情况： SCI

摘要： Modification of molecular structure of pesticides is a common method to seek new efficient broad-spectrum insecticides. This study focused on modifying the structure of deglycosylated or partially deglycosylated spinosad. Eight new macrolide derivatives had been synthesized by acylation. Their structures were characterized by H-1 NMR, C-13 NMR and MS techniques. Their fungicidal and insecticidal activities were also evaluated. The results showed that all compounds synthesized had excellent insecticidal activities against lepidoptera, coleoptera, diptera, hemiptera and nematoda. Compound 3e at the concentration of 100 mg/L presented 100% insecticidal activity against hemiptera (e.g. Myzus persicae) and compounds 3f and 3h loading 200 mu g presented certain inhibition against pseudomonas.

分类号：

  • 相关文献

[1]Synthesis, Structural Characterization, Insecticidal and Fungicidal Activity of (1H-1,2,4-Triazol-5-yl) carbamatest. Yang Dongyan,Che Chuanliang,Ma Yongqiang,Qin Zhaohai,Rui Changhui,Yan Xiaojing. 2016

[2]Insecticidal and fungicidal activities of chitosan and oligo-chitosan. Tan, TW. 2003

[3]Design, Synthesis and Antifungal/Insecticidal Evaluation of Novel Cinnamide Derivatives. Yang, Xiaoli,Xu, Yanjun,Qin, Zhaohai,Li, Bo,Wan, Shuqing,Yuan, Huizhu. 2011

[4]Synthesis and Biological Activities of 1,2,3-Thiadiazole Derivatives Containing 1,3,4-Thiadiazole Moiety. Wang Shouxin,Wang Shouxin,Zuo Xiang,Fan Zhijin,Zhang Zhengcai,Zhang Jufang,Xiong Lixia,Fu Yifeng,Fang Zhen,Wu Qingjun,Zhang Youjun. 2013

[5]Cloning and characterization of a novel Cry1A toxin from Bacillus thuringiensis with high toxicity to the Asian corn borer and other lepidopteran insects. Liang, Gemei,Li, Haitao,He, Kanglai,Song, Fuping,Feng, Xue,Zhang, Jie,Crickmore, Neil,Huang, Dafang.

[6]Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Analysis of 16 Kinds of Residual Antibiotics in Chicken Manure. Wu Dan,Zou De-Xun,Wu Dan,Han Mei-Lin,Wang Xu-Ming,Gao Min,Qiu Tian-Lei. 2017

[7]Polyketides from the plant endophytic fungus Cladosporium sp IFB3lp-2. Wuringege,Wei, Wei,Jiao, Rui-Hua,Yan, Tong,Zang, Le-Yun,Jiang, Rong,Tan, Ren-Xiang,Ge, Hui-Ming,Guo, Zhi-Kai. 2013

[8]Microwave Assistant Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing Pyridine Moiety. Sun, Guo-Xiang,Wu, Hong-Ke,Yang, Ming-Yan,Sun, Zhao-Hui,Liu, Xing-Hai,Shi, Yan-Xia,Li, Bao-Ju,Zhang, Yong-Gang. 2014

[9]Design, Synthesis, Biological Activities, and 3D-QSAR of New N,N '-Diacylhydrazines Containing 2-(2,4-dichlorophenoxy)propane Moiety. Liu, Xing-Hai,Weng, Jian-Quan,Tan, Cheng-Xia,Pan, Li,Ma, Yi,Li, Yong-Hong,Li, Zheng-Ming,Shi, Yan-Xia,Li, Bao-Ju,Zhang, Yong-Gang. 2011

[10]Synthesis and Fungicidal Activities of Azaindolyl Thiazoline Compounds. Xiao Yumei,Yuan Dekai,Zhang Zhenhua,Fu Bin,Yan Xiaojing,Yuan Huizhu. 2016

[11]Synthesis, Structure Characterization and Fungicidal Activity of 1,3-Disubstituted-1H-1,2,4-triazole-5-amines. Jia Changqing,Xu Yanjun,Liu Jiping,Qin Zhaohai,Su Wangcang. 2016

[12]Synthesis and Fungicidal Activity of 1,2,4-Triazole Derivatives Containing 2-Fluorophenyl Moiety. Tong Jianying,Sun Nabo,Liu Xinghai,Sun Nabo,Shi Yanxia,Li Baoju. 2012

[13]Synthesis and fungicidal activities of a novel series of 4-[3-(Pyrid-4-yl)-3-substituted phenyl acryloyl] morpholine. Yuan Hui-Zhu,Li Nan,Fu Bin,Xiao Yu-Mei,Ma Yong-Qiang,Qi Shu-Hua,Qin Zhao-Hai. 2007

[14]Transaldolase gene Ta167 enhances the biocontrol activity of Clonostachys rosea 67-1 against Sclerotinia sclerotiorum. Li, Shi-Dong,Sun, Man-Hong.

[15]Utilization of Chitosan-Lactide Copolymer Nanoparticles as Controlled Release Pesticide Carrier for Pyraclostrobin Against Colletotrichum gossypii Southw. Huang, Qi-Liang,Xu, Lei,Cao, Li-Dong,Li, Feng-Min,Wang, Xiang-Jing.

[16]Synthesis, Fungicidal Activity, and Structure-Activity Relationship of Spiro-Compounds Containing Macrolactam (Macrolactone) and Thiadiazoline Rings. Li, Jian-Jun,Liang, Xiao-Mei,Jin, Shu-Hui,Zhang, Jian-Jun,Chen, Fu-Heng,Wang, Dao-Quan,Yuan, Hui-Zhu,Qi, Shu-Hua.

[17]Design, synthesis and fungicidal activity of 11-alkoxyimino-5,6-dihydro-dibenzo[b,e] azepine-6-one derivatives. Xu, Yan-jun,Huang, Jia-xing,Liang, Xiao-mei,Zhang, Jian-jun,Wang, Dao-quan,Yan, Xiao-jing,Yuan, Hui-zhu.

[18]Synthesis and Evaluation of Novel N-(4 '-Arylpyrimidin-2 '-yl) Sulfonylurea Derivatives as Potential Antifungal Agents. Chen Wei,Li Yuxin,Wei Wei,Chen Youwei,Li Yonghong,Liu Jingbo,Li Zhengming,Chen Wei,Li Yuxin,Wei Wei,Chen Youwei,Liu Jingbo,Li Zhengming,Shi Yanxia,Li Baoju. 2015

[19]Quaternized Chitosan-Capped Mesoporous Silica Nanoparticles as Nanocarriers for Controlled Pesticide Release. Cao, Lidong,Zhang, Huirong,Cao, Chong,Zhang, Jiakun,Li, Fengmin,Huang, Qiliang. 2016

[20]Synthesis and Fungicidal Activities of Aryl Thiocarbamic Acid-5-aryl-2-furanmethyl Ester. Li Yang,Yang Xinling,Miao Hongjian,Ling Yun,Li Baoju,Shi Yanxia,Li Yang. 2011

作者其他论文 更多>>

微信小程序