Association of T1740C polymorphism of L-FABP with meat quality traits in Junmu No. 1 white swine
文献类型: 外文期刊
第一作者: Zhang, Y. H.
作者: Zhang, Y. H.;Dai, L. S.;Ma, T. H.;Li, F. J.;Liu, D. F.;Gao, Y.;Zhang, J. B.;Zhang, Y. H.;Guo, J.;Sun, B. X.;Gao, Y.;Zhang, J. B.;Wang, S. Z.;Zhang, S. M.
作者机构:
关键词: Swine;L-FABP;Intron 1;Single nucleotide polymorphism;Marbling;Intramuscular fat
期刊名称:GENETICS AND MOLECULAR RESEARCH ( 影响因子:0.764; 五年影响因子:0.912 )
ISSN: 1676-5680
年卷期: 2013 年 12 卷 1 期
页码:
收录情况: SCI
摘要: This study was designed to investigate a single nucleotide polymorphism in intron 1 of the liver fatty acid-binding protein (L-FABP) gene in 156 Junmu No. 1 white swine using PCR-single-strand conformational polymorphism. The association between the polymorphism and meat quality traits was also studied. The cloning and sequencing results indicated that the polymorphism in intron 1 was due to a T -> C mutation at position 1740 of L-FABP, yielding three genotypes (TT, TC, and CC). Association analysis revealed that the polymorphism had a significant effect on marbling (P < 0.05): genotype CC had more marbling than TC, and TC had more marbling than TT. The polymorphism also had a highly significant effect on intramuscular fat content (P < 0.01). Genotypes CC and TC had higher intramuscular fat content than TT; there was no significant difference between CC and TC (P > 0.05). However, no significant conclusions concerning other traits could be drawn. We tentatively conclude that L-FABP is a candidate gene or a quantitative trait locus-linked gene associated with meat quality traits.
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