Expression of HMGR and corresponding cholesterol content in tissues of two pig breeds

文献类型: 外文期刊

第一作者: Liu, G. -F.

作者: Liu, G. -F.;Fang, W-N;Lin, H. -C.;Fu, J-L;Wang, A. -G.;Liu, G. -F.;Fu, J-L;Wang, A. -G.;Lin, H. -C.;Wang, X. -F.

作者机构:

关键词: 3-hydroxy-3-methylglutaryl-CoA reductase;cholesterol;mRNA expression;pig

期刊名称:ANIMAL ( 影响因子:3.24; 五年影响因子:3.223 )

ISSN: 1751-7311

年卷期: 2009 年 3 卷 10 期

页码:

收录情况: SCI

摘要: The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) is an essential enzyme in cholesterol biosynthesis. To study the expression of HMGR and corresponding cholesterol content in liver, adipose and muscle, six Chinese local breed (Huai pig) and Landrace pigs were selected. The results indicated that significant differences of cholesterol content in adipose (P < 0.01), liver (P < 0.05) and muscle (P < 0.01) tissues were detected between pigs of differing genetic backgrounds. H M G R mRNA expression were noted for adipose, liver and muscle of the two vastly differing genetics. Moreover cholesterol content differed (P < 0.01) among tissues across breed. Likewise, HMGR mRNA expression was different between adipose and liver tissues, muscle and liver tissues in both breeds; however, no difference was noted between adipose and muscle tissues. Results from this study indicate that cholesterol content and HMGR mRNA expression are higher in Huai pig tissues suggesting this gene is expressed in a breed- and tissue-dependent manner in pigs. Understanding the causes of variation in HMGR gene expression may provide crucial information about cholesterol biosynthesis.

分类号:

  • 相关文献

[1]Effect of mevalonic acid on cholesterol synthesis in bovine intramuscular and subcutaneous adipocytes. Liu, Xiaomu,You, Wei,Cheng, Haijian,Song, Enliang,Wan, Fachun,Han, Hong,Liu, Guifen,Liu, Xiaomu,You, Wei,Cheng, Haijian,Song, Enliang,Wan, Fachun,Han, Hong,Liu, Guifen,Zhang, Qingfeng.

[2]Cloning, expression, and polymorphism of the ECI1 gene in various pig breeds. Lu Yun-feng,Zhang Bo,Li Qing-gang,Wang Zhi-xiu,Zhang Hao,Wu Ke-liang,Lu Yun-feng,Chen Ji-bao,Li Qing-gang. 2017

[3]Expression and genome polymorphism of ACSL1 gene in different pig breeds. Li, Qinggang,Tao, Zhu,Shi, Lihua,Ban, Dongmei,Zhang, Bo,Yang, Yuzeng,Zhang, Hao,Wu, Changxin,Li, Qinggang.

[4]Two transcripts of HMG-CoA reductase related with developmental regulation from Scylla paramamosain: Evidences from cDNA cloning and expression analysis. Zhao, Ming,Jiang, Keji,Song, Wei,Ma, Chunyan,Wang, Jing,Meng, Yongyong,Wei, Hongqing,Qiao, Zhenguo,Zhang, Fengying,Ma, Lingbo,Zhao, Ming,Wang, Jing,Meng, Yongyong,Wei, Hongqing,Chen, Kai.

[5]Excess dietary cholesterol may have an adverse effect on growth performance of early post-larval Litopenaeus vannamei. Niu, Jin,Lin, Hei-Zhao,Chen, Peng-Fei,Tian, Li-Xia,Liu, Yong-Jian,Yang, Hui-Jun,Liang, Gui-Ying. 2012

[6]Dietary values of astaxanthin and canthaxanthin in Penaeus monodon in the presence and absence of cholesterol supplementation: effect on growth, nutrient digestibility and tissue carotenoid composition. Niu, Jin,Li, Chun-Hou,Chen, Xu,Huang, Zhong,Lin, Hei-Zhao,Liu, Yong-Jian,Tian, Li-Xia. 2012

[7]Effects of dietary taurine on egg production, egg quality and cholesterol levels in Japanese quail. Wang, Fu-Rong,Zhang, Xiao-Ming,Tong, Jian-Ming,Xie, Zhong-Guo,Wang, Fu-Rong,Zhang, Xiao-Ming,Tong, Jian-Ming,Xie, Zhong-Guo,Wang, Fu-Rong,Dong, Xiao-Fang,Tong, Jian-Ming,Zhang, Qi. 2010

[8]Cholesterol exacerbates Mycoplasma hyopneumoniae-induced apoptosis via stimulating proliferation and adhesion to porcine alveolar macrophages. Liu, Maojun,Hu, Yun,Liu, Jie,Jia, Yimin,Zhao, Ruqian,Liu, Maojun,Liu, Beibei,Shao, Guoqing,Jia, Yimin,Zhao, Ruqian,Du, Gaimei,Minion, F. Chris,Shao, Guoqing. 2017

[9]Comparison effect of dietary astaxanthin and beta-carotene in the presence and absence of cholesterol supplementation on growth performance, antioxidant capacity and gene expression of Penaeus monodon under normoxia and hypoxia condition. Niu, Jin,Li, Chun-Hou,Chen, Xu,Huang, Zhong,Lin, Hei-Zhao,Liu, Yong-Jian,Tian, Li-Xia,Wen, Hua. 2014

[10]Identification of differentially expressed genes in Tetrahmena thermophila in response to dichlorodiphenyltrichloroethane (DDT) by suppression subtractive hybridization. Miao, W,Yu, T,Orias, E,Wan, ML,Fu, CJ.

[11]Detection of virgin coconut oil adulteration with animal fats using quantitative cholesterol by GC x GC-TOF/MS analysis. Xu, Baocheng,Li, Peiwu,Ma, Fei,Wang, Xiuping,Chen, Ran,Yang, Qingqing,Zhang, Wen,Zhang, Qi,Li, Peiwu,Ma, Fei,Wang, Xiuping,Chen, Ran,Xu, Baocheng,Li, Peiwu,Yang, Qingqing,Zhang, Wen,Zhang, Qi,Li, Peiwu,Ma, Fei,Chen, Ran,Yang, Qingqing,Xu, Baocheng,Li, Peiwu,Ma, Fei,Wang, Xiuping,Zhang, Wen,Zhang, Qi,Matthaeus, Bertrand,Xu, Baocheng,Xu, Baocheng.

[12]The effect of diet and host genotype on ceca microbiota of Japanese quail fed a cholesterol enriched diet. Liu, Shasha,Zhang, Hongfu,Liu, Shasha,Bennett, Darin C.,Kim, Ji-Eun,Cheng, Kimberly M.,Tun, Hein M.,Leung, Frederick C.. 2015

[13]Effects of graded replacement of soybean meal by sunflower seed meal in laying hen diets on hen performance, egg quality, egg fatty acid composition, and cholesterol content. Shi, S. R.,Lu, J.,Tong, H. B.,Zou, J. M.,Wang, K. H.. 2012

[14]Mung Bean Decreases Plasma Cholesterol by Up-regulation of CYP7A1. Yao, Yang,Hao, Liu,Shi, Zhenxing,Wang, Lixia,Cheng, Xuzhen,Wang, Suhua,Ren, Guixing. 2014

[15]Entry of Bombyx mori nucleopolyhedrovirus into BmN cells by cholesterol-dependent macropinocytic endocytosis. Huang, Jinshan,Hao, Bifang,Cheng, Chen,Liang, Fei,Shen, Xingjia,Huang, Jinshan,Hao, Bifang,Shen, Xingjia,Cheng, Xiaowen.

[16]Decreased saturated fatty acids, total cholesterol and LDL-C in sdd17 mice. Chen, Yong-Gang,Yan, Bo-Wen,Gou, Ke-Mian,Cao, Wen-Guang,Ma, Shu-Yu. 2013

[17]A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts. Zhu, Wei,Deng, Xiangyi,Peng, Jinming,Li, Chunmei,Li, Chunmei,Zou, Bo. 2017

[18]Screening and characterization of lactic acid bacterial strains that produce fermented milk and reduce cholesterol levels. Guan, Xuefang,Xu, Qingxian,Zheng, Yi,Qian, Lei,Lin, Bin. 2017

[19]Effect of postharvest L-arginine or cholesterol treatment on the quality of green asparagus (Asparagus officinalis L.) spears during low temperature storage. Wang, Xiangyang,Gu, Shuang,Chen, Beili,Huang, Jianying,Xing, Jianrong. 2017

[20]Comparison of the activities of hydrophilic anthocyanins and lipophilic tocols in black rice bran against lipid oxidation. Zhang, Xiumei,Zhang, Xiumei,Shen, Yixiao,Prinyawiwatkul, Witoon,King, Joan M.,Xu, Zhimin.

作者其他论文 更多>>