Complete genome sequence analysis of the fish pathogen Flavobacterium columnare provides insights into antibiotic resistance and pathogenicity related genes
文献类型: 外文期刊
第一作者: Zhang, Yulei
作者: Zhang, Yulei;Zhao, Lijuan;Lin, Li;Zhao, Lijuan;Chen, Wenjie;Huang, Yunmao;Yang, Ling;Sarathbabu, V.;Wu, Zaohe;Li, Jun;Lin, Li;Nie, Pin;Li, Jun;Li, Jun;Lin, Li;Lin, Li
作者机构:
关键词: Flavobacterium columnare;Complete genome;Antibiotic resistance genes;Pathogenicity related genes
期刊名称:MICROBIAL PATHOGENESIS ( 影响因子:3.738; 五年影响因子:3.663 )
ISSN: 0882-4010
年卷期: 2017 年 111 卷
页码:
收录情况: SCI
摘要: We analyzed here the complete genome sequences of a highly virulent Flavobacterium columnare Pf1 strain isolated in our laboratory. The complete genome consists of a 3,171,081 bp circular DNA with 2784 predicted protein-coding genes. Among these, 286 genes were predicted as antibiotic resistance genes, including 32 RND-type efflux pump related genes which were associated with the export of amino glycosides, indicating inducible aminoglycosides resistances in F. columnare. On the other hand, 328 genes were predicted as pathogenicity related genes which could be classified as virulence factors, gliding motility proteins, adhesins, and many putative secreted proteases. These genes were probably involved in the colonization, invasion and destruction of fish tissues during the infection of E columnare. Apparently, our obtained complete genome sequences provide the basis for the explanation of the interactions between the F. columnare and the infected fish. The predicted antibiotic resistance and pathogenicity related genes will shed a new light on the development of more efficient preventional strategies against the infection of E columnare, which is a major worldwide fish pathogen. (C) 2017 Elsevier Ltd. All rights reserved.
分类号:
- 相关文献
作者其他论文 更多>>
-
Saline-alkali soil amended with biochar derived from maricultural-solid-waste: Ameliorative effect and mechanism
作者:Cai, Yongkun;Wu, Lele;Song, Xiefa;Li, Xian;Ren, Liping;Wu, Lele;Li, Jun;Yang, Shengmao
关键词:Maricultural-solids-waste; Biochar; Saline-alkali soil; Salicornia europaea L
-
Screening of Active Substances Regulating Alzheimer's Disease in Ginger and Visualization of the Effectiveness on 6-Gingerol Pathway Targets
作者:Pan, Yecan;Li, Zishu;Zhao, Xiaoyu;Du, Yang;Zhang, Lin;Lu, Yushun;Yang, Ling;Cao, Yilin;Qiu, Jing;Qian, Yongzhong;Pan, Yecan;Li, Zishu;Zhao, Xiaoyu;Du, Yang;Zhang, Lin;Lu, Yushun;Yang, Ling;Cao, Yilin;Qiu, Jing;Qian, Yongzhong
关键词:6-Gingerol; ginger; Alzheimer's disease (AD); network pharmacology; molecular dynamics (MD)
-
Carbon emission oriented life cycle assessment and optimization strategy for meat supply chain
作者:Zhang, Xiaoshuan;Jiang, Dongsheng;Li, Jun;Zhang, Mengjie;Zhao, Qinan
关键词:Meat supply chain; GHGs; Energy consumption; Optimization strategy
-
Quality Evaluation and Identification of Phyllanthi fructus (Yuganzi) Based on the Spectrum-Effect Relationship
作者:Zhou, Weiwei;Liu, Ling;Li, Jun;Shi, Dongdong;Li, Xiumei;Wu, Bencheng
关键词:Yuganzi; spectrum-activity relationship; antioxidant effects; quality evaluation; identification
-
Dynamics of antibiotic resistance genes and the association with bacterial community during pig manure composting with chitin and glucosamine addition
作者:Wang, Bo;Sa, Chula;Zhang, Chunhua;Li, Wenting;Sun, Haizhou;Wang, Bo;Sa, Chula;Zhang, Chunhua;Li, Wenting;Sun, Haizhou;Wang, Bo;Sa, Chula;Zhang, Chunhua;Li, Wenting;Sun, Haizhou;Chen, Wenjie;Gao, Xin;Chang, Su;Wei, Yuquan;Li, Ji;Shi, Xiong;Zhang, Longli
关键词:antibiotic resistance genes (ARGs); mobile genes elements (MGEs); bacterial communities; chitin; glucosamine; composting
-
Effects of bisphenol A and tauroursodeoxycholic acid on maturation of porcine oocytes and parthenogenetic development of embryos
作者:Yang, Ling;Zhang, Qiongao;Zhang, Leying;Zhang, Qiongao;Cui, Maosheng;Ma, Yong
关键词:bisphenol A; embryo; oocyte; pig; tauroursodeoxycholic acid
-
The enhancement of wastewater purification efficiency in ecological floating bed aquaculture through alginate oligosaccharide treatment
作者:Xu, Xueren;Li, Cong;Li, Jun;Wang, Feng;Zhou, Sheng
关键词:Algal oligosaccharide; Ecological floating bed; Water spinach; Purification efficiency