Complete genome sequence analysis of the fish pathogen Flavobacterium columnare provides insights into antibiotic resistance and pathogenicity related genes

文献类型: 外文期刊

第一作者: Zhang, Yulei

作者: Zhang, Yulei;Zhao, Lijuan;Lin, Li;Zhao, Lijuan;Chen, Wenjie;Huang, Yunmao;Yang, Ling;Sarathbabu, V.;Wu, Zaohe;Li, Jun;Lin, Li;Nie, Pin;Li, Jun;Li, Jun;Lin, Li;Lin, Li

作者机构:

关键词: Flavobacterium columnare;Complete genome;Antibiotic resistance genes;Pathogenicity related genes

期刊名称:MICROBIAL PATHOGENESIS ( 影响因子:3.738; 五年影响因子:3.663 )

ISSN: 0882-4010

年卷期: 2017 年 111 卷

页码:

收录情况: SCI

摘要: We analyzed here the complete genome sequences of a highly virulent Flavobacterium columnare Pf1 strain isolated in our laboratory. The complete genome consists of a 3,171,081 bp circular DNA with 2784 predicted protein-coding genes. Among these, 286 genes were predicted as antibiotic resistance genes, including 32 RND-type efflux pump related genes which were associated with the export of amino glycosides, indicating inducible aminoglycosides resistances in F. columnare. On the other hand, 328 genes were predicted as pathogenicity related genes which could be classified as virulence factors, gliding motility proteins, adhesins, and many putative secreted proteases. These genes were probably involved in the colonization, invasion and destruction of fish tissues during the infection of E columnare. Apparently, our obtained complete genome sequences provide the basis for the explanation of the interactions between the F. columnare and the infected fish. The predicted antibiotic resistance and pathogenicity related genes will shed a new light on the development of more efficient preventional strategies against the infection of E columnare, which is a major worldwide fish pathogen. (C) 2017 Elsevier Ltd. All rights reserved.

分类号:

  • 相关文献

[1]Expression profiling analysis of immune-related genes in channel catfish (Ictalurus punctatus) skin mucus following Flavobacterium columnare challenge. Ren, Yichao,Li, Chao,Zhao, Honggang,Peatman, Eric,Su, Baofeng.

[2]Changes in tetracycline partitioning and bacteria/phage-comediated ARGs in microplastic-contaminated greenhouse soil facilitated by sophorolipid. Sun, Mingming,Liu, Manqiang,Jiao, Jiaguo,Liu, Kuan,Zhao, Yuanchao,Wu, Jun,Hu, Feng,Ye, Mao,Jiang, Xin,Jiao, Wentao,Feng, Yanfang,Yu, Pingfeng,He, Xiaojia. 2018

[3]Long-term field application of sewage sludge increases the abundance of antibiotic resistance genes in soil. Chen, Qinglin,An, Xinli,Li, Hu,Su, Jianqiang,Zhu, Yong-Guan,Ma, Yibing,Zhu, Yong-Guan.

[4]Dissemination of antibiotic resistance genes and their potential removal by on-farm treatment processes in nine swine feedlots in Shandong Province, China. Ben, Weiwei,Qiang, Zhimin,Wang, Jian,Wang, Jian,Pan, Xun.

[5]Impact of bioaccessible pyrene on the abundance of antibiotic resistance genes during Sphingobium sp.- and sophorolipid-enhanced bioremediation in soil. Sun, Mingming,Wu, Jun,Shen, Fangyuan,Tian, Da,Liu, Kuan,Hu, Feng,Li, Huixin,Sun, Mingming,Ye, Mao,Jiang, Xin,Feng, Yanfang,Yang, Linzhang,Kengara, Fredrick Orori.

[6]Effects of manure and mineral fertilization strategies on soil antibiotic resistance gene levels and microbial community in a paddy-upland rotation system. Lin, Hui,Sun, Wanchun,Fu, Jianrong,Ma, Junwei,Zhang, Zulin,Chapman, Stephen J.,Freitag, Thomas E.,Zhang, Xin.

[7]Persistence of antibiotic resistance genes and bacterial community changes in drinking water treatment system: From drinking water source to tap water. Su, Hao-Chang,Su, Hao-Chang,Liu, You-Sheng,Pan, Chang-Gui,Chen, Jun,He, Liang-Ying,Ying, Guang-Guo,Ying, Guang-Guo. 2018

[8]Positive relationship detected between soil bioaccessible organic pollutants and antibiotic resistance genes at dairy farms in Nanjing, Eastern China. Sun, Mingming,Wu, Jun,Tian, Da,Shen, Fangyuan,Liu, Kuan,Hu, Feng,Li, Huixin,Sun, Mingming,Ye, Mao,Jiang, Xin,Feng, Yanfang,Yang, Linzhang,Wan, Jinzhong,Kengara, Fredrick Orori.

[9]Calcined Eggshell Waste for Mitigating Soil Antibiotic-Resistant Bacteria/Antibiotic Resistance Gene Dissemination and Accumulation in Bell Pepper. Ye, Mao,Jiang, Xin,Sun, Mingming,Liu, Manqiang,Tian, Da,Liu, Kuan,Wu, Jun,Sun, Mingming,Schwab, Arthur P.,Feng, Yanfang,Li, Xu,Wan, Jinzhong.

[10]Prevalence of antibiotic resistance genes in soils after continually applied with different manure for 30 years. Peng, Shuang,Feng, Youzhi,Wang, Yiming,Chu, Haiyan,Lin, Xiangui,Guo, Xisheng.

[11]Occurrence and temporal variation of antibiotic resistance genes (ARGs) in shrimp aquaculture: ARGs dissemination from farming source to reared organisms. Su, Haochang,Hu, Xiaojuan,Xu, Wujie,Xu, Yu,Li, Zhuojia,Wen, Guoliang,Cao, Yucheng,Liu, Yousheng,Liu, Shan,Xu, Xiangrong.

[12]Genetic characterization of the complete genome of a mutant canine parvovirus isolated in China. Li, Chuanfeng,Tang, Jingyu,Chen, Zongyan,Li, Qi,Wang, Quan,Meng, Chunchun,Liu, Guangqing,Tang, Jingyu,Wang, Yong,Li, Qi,Huang, Zhenhua. 2018

[13]Sequencing and comparative analysis of a pig bovine viral diarrhea virus genome. Xu, Xingran,Zhang, Qingchan,Yu, Xinglong,Liang, Long,Xiao, Chang,Xiang, Hua,Tu, Changchun. 2006

[14]Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp strain fd1-xmd. Yu, Yucong,Tang, Biao,Dai, Ruixue,Zhang, Bo,Chen, Liqiang,Zhao, Guoping,Ding, Xiaoming,Tang, Biao,Yang, Hua,Zhao, Guoping. 2018

[15]Molecular characteristics of the complete genome of a J-subgroup avian leukosis virus strain isolated from Eurasian teal in China. Zeng, Xiangwei,Hao, Ruijun,Liu, Wansi,Han, Chunyan,Zeng, Xiangwei,Gao, Yulong,Li, Delong,Hao, Ruijun,Liu, Wansi,Han, Chunyan,Gao, Honglei,Qi, Xiaole,Wang, Yongqiang,Wang, Xiaomei,Liu, Lanlan.

[16]Complete sequence and phylogenetic analysis of a porcine bocavirus strain swBoV CH437. Wang, Enli,Liu, Wei,Yang, Bin,Liu, Jixing,Lan, Xi,Wang, Enli,Ma, Xiaojun.

[17]Complete mitochondrial genome of the Lampetra japonica. Huo, Tang-Bin,Peng, Lina,Lu, Jianguo,Jiang, Zuo-Fa,Peng, Lina.

[18]Complete genome of Thauera humireducens SgZ-1, a potential bacterium for environmental remediation and wastewater treatment. Ma, Chen,Zhang, Qun,Yang, Guiqin,Zhuang, Li,Zhou, Shungui.

[19]Complete genome sequence and pathogenesis of bovine viral diarrhea virus JL-1 isolate from cattle in China. Zhang, Shuqin,Tan, Bin,Wang, Fengxue,Guo, Li,Wen, Yongjun,Cheng, Shipeng,Wu, Hua,Ding, Yulin,Wu, Hua. 2014

[20]Detection and complete genome characteristics of Posavirus 1 from pigs in China. Chen, Jianfei,Lu, Manman,Cao, Liyan,Zhu, Xiangdong,Zhang, Xin,Shi, Da,Shi, Hongyan,Liu, Jianbo,Feng, Li,Ma, Tianxin. 2018

作者其他论文 更多>>