Facile fabrication of graphene oxide loaded with silver nanoparticles as antifungal materials
文献类型: 外文期刊
第一作者: Cui, Jianghu
作者: Cui, Jianghu;Yang, Yunhua;Zheng, Mingtao;Liu, Yingliang;Xiao, Yong;Lei, Bingfu;Chen, Wei
作者机构:
关键词: graphene oxide;silver nanoparticles;antifungal;oxidative stress;apoptosis;hemolysis
期刊名称:MATERIALS RESEARCH EXPRESS ( 影响因子:1.62; 五年影响因子:1.618 )
ISSN: 2053-1591
年卷期: 2014 年 1 卷 4 期
页码:
收录情况: SCI
摘要: Graphene oxide loaded silver nanoparticles (GO-Ag) were synthesized using a simple method. Our evidence showed that silver nanoparticles (Ag NPs) were successfully loaded on the surface of graphene oxide sheets. The antifungal property of GO-Ag composites was investigated. The results revealed that the obtained GO-Ag composites exhibit enhanced antifungal property in comparison with that of Ag NPs. The toxicity of GO-Ag and Ag NPs were systematically evaluated. The study of cell viability, lactate dehydrogenase, reactive oxygen species, apoptosis/necrosis and hemolysis revealed that GO-Ag composites have lower cytotoxicity and better blood compatibility than Ag NPs. Therefore, these findings provide nanotoxicological information regarding GO-Ag composites which may be alternative antifungal materials in their application of biomedical fields.
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