Antimycins A(19) and A(20), two new antimycins produced by marine actinomycete Streptomyces antibioticus H74-18

文献类型： 外文期刊

第一作者： Xu, Lin-Ya

作者： Xu, Lin-Ya;Quan, Xue-Sheng;Zhou, Guang-Xiong;Jiang, Ren-Wang;Yao, Xin-Sheng;Wang, Chen;Sheng, Hui-Fang;Lin, Bi-Run

作者机构：

关键词： actinomycete;antifungal activity;antimycins A(19) and A(20);Streptomyces antibioticus;X-ray diffraction

期刊名称：JOURNAL OF ANTIBIOTICS （ 影响因子：2.649； 五年影响因子：2.772 ）

ISSN： 0021-8820

年卷期： 2011 年 64 卷 10 期

页码：

收录情况： SCI

摘要： Two new antimycin antibiotics, that is antimycins A(19) (1) and A(20) (2), were isolated from a cultured broth of marine actinomycete Streptomyces antibioticus H74-18 together with antimycins A(1a) (3a) and A(1b) (3b), A(2a) (4), A(3a) (5a) and A(3b) (5b). Their structures were determined by spectroscopic methods in combination with X-ray diffraction. Antimycin A(19) possessed a chiral acyl chain and an alkyl branch. The absolute configuration of chiral acyl chain in 1 was determined by X-ray diffraction analysis. Antimycin A(20) (2) has the shortest and simplest acetoxy acyl chain in the antimycins family. All the antimycins (1-5) showed potential antifungal activities against Candida albicans with MIC of about 5-10 mu g ml(-1). The Journal of Antibiotics (2011) 64, 661-665; doi:10.1038/ja.2011.65; published online 17 August 2011

分类号：

  • 相关文献

[1]Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09. Wang, Fan,Fu, Shu-Na,Bao, Yi-Xuan,Yang, Yu,Zhou, Guang-Xiong,Shen, Hui-Fang,Lin, Bi-Run. 2017

[2]Neoantimycins A and B, Two Unusual Benzamido Nine-Membered Dilactones from Marine-Derived Streptomyces antibioticus H12-15. Hu, Chen,Zhou, Shi-Wen,Chen, Fang,Zheng, Xin-Heng,Zhou, Guang-Xiong,Shen, Hui-Fang,Lin, Bi-Run.

[3]A novel antibiotic produced by streptomyces noursei Da07210. Wu, Xiaopeng,Huang, Huiqin,Sun, Qianguang,Peng, Jie,Zhu, Jun,Bao, Shixiang,Chen, Guangying. 2009

[4]Green synthesis of gold nanoparticles using Citrus maxima peel extract and their catalytic/antibacterial activities. Yuan, Chun-Gang,Huo, Can,Gui, Bing,Cao, Wei-Ping. 2017

[5]A new fungicide produced by a Streptomyces sp GAAS7310. Chen, GY,Lin, BR,Lin, YC,Xie, FC,Lu, W,Fong, WF. 2005

[6]New Cytotoxic Alkylated Anthraquinone Analogues from a Soil Actinomycete Streptomyces sp WS-13394. Wu, Zhao-Yuan,Fang, Wei,Shi, Li-Qiao,Wan, Zhong-Yi,Min, Yong,Wang, Kai-Mei. 2014

[7]Four new anthraquinones from a soil actinomycete Streptomyces sp WS-13394 and their bioactivities. Wu, Zhaoyuan,Zhang, Yani,Fang, Wei,Shi, Liqiao,Wan, Zhongyi. 2018

[8]Synthesis and Characterization of Gelatin-Polydimethylsiloxane Graft Copolymers. Zhang, Meng,Xia, Yongmei,Li, Tianduo,Zhang, Meng,Zhang, Qingsi,Li, Tianduo,Wu, Yuanjuan. 2011

[9]Synergetic dual recognition and separation of the fungicide carbendazim by using magnetic nanoparticles carrying a molecularly imprinted polymer and immobilized beta-cyclodextrin. Li, Shuhuai,Wu, Xuejin,Zhang, Qun,Li, Pingping,Li, Shuhuai,Wu, Xuejin,Zhang, Qun,Li, Pingping.

[10]An electrochemiluminescence aptasensor switch for aldicarb recognition via ruthenium complex-modified dendrimers on multiwalled carbon nanotubes. Li, Shuhuai,Liu, Chunhua,Han, Bingjun,Luo, Jinhui,Yin, Guihao,Li, Shuhuai,Liu, Chunhua,Han, Bingjun,Luo, Jinhui,Yin, Guihao. 2017

[11]Adsorption of nitrogen and oxygen in cobalt (II)-exchanged zeolite A. Wu, Jian,Zhu, Jiang,Wang, Yu,Liu, Ruibin,Meng, Changgong,Shang, Yunshuai. 2010

[12]Crystallization and X-ray diffraction analysis of native and selenomethionine-substituted PhyH-DI from Bacillus sp HJB17. Lu, Fang,Zhang, Bei,Liu, Yong,Song, Ying,Guo, Gangxing,Feng, Duo,Gao, Wei,Lu, Fang,Guo, Sujuan,Huang, Huoqing,Yang, Peilong,Yao, Bin. 2017

[13]Design, Synthesis, Crystal Structure, Insecticidal Activity, Molecular Docking, and QSAR Studies of Novel N-3-Substituted Imidacloprid Derivatives. Wang, Mei-Juan,Zhao, Xiao-Bo,Wu, Dan,Liu, Ying-Qian,Zhang, Yan,Nan, Xiang,Liu, Huanxiang,Yan, Li-Ting,Yu, Hai-Tao,Hu, Guan-Fang. 2014

[14]Design, semisynthesis and insecticidal activity of novel podophyllotoxin derivatives against Brontispa longissima in vivo. Liu, Ying-Qian,Zhao, Yong-Long,Zhou, Xing-Wen,Yang, Liu,Feng, Gang. 2012

[15]Secondary metabolites of the lichen-associated fungus Apiospora montagnei. Wang, Hao,Umeokoli, Blessing O.,Eze, Peter,Liu, Zhen,Proksch, Peter,Umeokoli, Blessing O.,Eze, Peter,Heering, Christian,Janiak, Christoph,Mueller, Werner E. G.,Orfali, Raha S.,Hartmann, Rudolf,Dai, Haofu,Lin, Wenhan.

[16]Coordination Frameworks based on 3,5-Bis(imidazole-1-yl)pyridine and Aromatic Dicarboxylate Ligands: Synthesis, Crystal Structures, and Photoluminescent Properties. Xu, Jiakun,Sun, Mi,Xu, Jiakun,Yan, Xincheng,Bi, Caifeng,Sun, Xiaochun,Yang, Lirong.

[17]A new cyclohexapeptide, penitropeptide and a new polyketide, penitropone from the endophytic fungus Penicillium tropicum. Zeng, Yanbo,Dai, Haofu,Zeng, Yanbo,Wang, Hao,Kamdem, Ramsay S. T.,Liu, Zhen,Proksch, Peter,Kamdem, Ramsay S. T.,Orfali, Raha S.,Makhloufi, Gamall,Janiak, Christoph.

[18]Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety. Sun, Guo-Xiang,Sun, Zhao-Hui,Yang, Ming-Yan,Wu, Hong-Ke,Weng, Jian-Quan,Tan, Cheng-Xia,Liu, Xing-Hai,Shi, Yan-Xia,Li, Bao-Ju,Zhang, Yong-Gang. 2014

[19]Three Non-Aspartate Amino Acid Mutations in the ComA Response Regulator Receiver Motif Severely Decrease Surfactin Production, Competence Development, and Spore Formation in Bacillus sublilis. Wang Xiaoyu,Luo, Chuping,Liu, Youzhou,Nie, Yafeng,Liu, Yongfeng,Zhang, Rongsheng,Chen, Zhiyi. 2010

[20]Anti-Phytopathogenic and Cytotoxic Activities of Crude Extracts and Secondary Metabolites of Marine-Derived Fungi. Zhao, Dong-Lin,Wang, Dan,Tian, Xue-Ying,Li, Yi-Qiang,Zhang, Cheng-Sheng,Cao, Fei. 2018

作者其他论文 更多>>

微信小程序