Effect of genistein on antioxidative defence system and membrane fluidity in chick skeletal muscle cells

文献类型： 外文期刊

第一作者： Jiang, Z. Y.

作者： Jiang, Z. Y.;Jiang, S. Q.;Lin, Y. C.;Ma, X. Y.;Xi, P. B.;Cao, T.;Wang, X. Q.

作者机构：

关键词： genistein;lipid peroxidation;membrane fluidity;antioxidation;chick skeletal muscle cells

期刊名称：ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES （ 影响因子：2.509； 五年影响因子：2.604 ）

ISSN： 1011-2367

年卷期： 2008 年 21 卷 8 期

页码：

收录情况： SCI

摘要： This study was conducted to investigate the protective effect of genistein on the antioxidative defence system and membrane fluidity in chick skeletal muscle cells after supplementation with 0, 20, 40, and 80 mu mol/L genistein in 50 mu mol/L FeSO4/H2O2 treated cells for 24 h. Genistein supplementation recovered the decreased activity of total superoxide dismutase induced by FeSO4/ H2O2, significantly increased glutathione peroxidase activity (p < 0.05) and decreased malondialdehyde production (p < 0.05). The treatment of 80 mu mol genistein in FeSO4/H2O2 treated cells decreased the secretion of creatine kinase (p < 0.05). Fluorescence polarization values and microviscosities observed with FeSO4/H2O2 treated cells were significantly higher than those observed with no FeSO4/H2O2 treated cells. The addition of 80 mu mol/L genistein improved the increased fluorescence polarization value (p < 0.05) caused by FeSO4/H2O2 treatment. The microviscosity value was significantly decreased by adding genistein (p < 0.05). In conclusion, genistein protected skeletal muscle cells from oxidative damage by improving antioxidative status and membrane fluidity.

分类号：

  • 相关文献

[1]Effects of Daidzein or Genistein on Proliferation and Antioxidation of Mammary Epithelial Cell of Dairy Cow in vitro. Liu, Chunlong,Li, Zhongqiu,Feng, Xingjun. 2012

[2]Epigallocatechin-3-gallate affects the growth of LNCaP cells via membrane fluidity and distribution of cellular zinc. Yang, Jun-guo,Sun, Shi-li,Zhang, Lan-cui,He, Guo-qing,Ruan, Hui,Shen, Sheng-rong,Yu, Hai-ning,Sun, Shi-li,Das, Undurti N.. 2009

[3]Modification of membrane properties and fatty acids biosynthesis-related genes in Escherichia coli and Staphylococcus aureus: Implications for the antibacterial mechanism of naringenin. Wang, Lang-Hong,Zeng, Xin-An,Brennan, Charles S.,Wang, Man-Sheng,Brennan, Charles S.,Gong, Deming. 2018

[4]Effect of exogenous silicon (Si) on H+-ATPase activity, phospholipids and fluidity of plasma membrane in leaves of salt-stressed barley (Hordeum vulgare L.). Liang, Yongchao,Zhang, Wenhua,Chen, Qin,Liu, Youliang,Ding, Ruixing. 2006

[5]Bidirectional Estrogen-Like Effects of Genistein on Murine Experimental Autoimmune Ovarian Disease. Ding, Qiao,Wang, Yuxiao,Li, Na,Hu, Jielun,Nie, Shaoping,Zhu, Kexue,Wang, Sunan,Zhu, Fan. 2016

[6]Genistein-Specific G6DT Gene for the Inducible Production of Wighteone in Lotus japonicus. Liu, Jinyue,Jiang, Wenbo,Xia, Yaying,Pang, Yongzhen,Liu, Jinyue,Jiang, Wenbo,Xia, Yaying,Pang, Yongzhen,Liu, Jinyue,Liu, Jinyue,Wang, Xuemin,Pang, Yongzhen,Shen, Guoan. 2018

[7]Effects of Dietary Genistein on Plasma and Liver Lipids, Hepatic Gene Expression, and Plasma Metabolic Profiles of Hamsters with Diet-Induced Hyperlipidemia. Tang, Chaohua,Zhang, Kai,Zhao, Qingyu,Zhang, Junmin.

[8]Functional ionic liquids as effective catalysts for the preparation of genistein and daidzein. Hu, Xiaomei,Hu, Baozhong,Zhang, Bixian,Yuan, Zan. 2013

[9]Production of isoflavone genistein in transgenic IFS tobacco roots and its role in stimulating the development of arbuscular mycorrhiza. Tan, Zhijing,Hu, Yuanlei,Lin, Zhongping,Liu, Rongrong. 2012

[10]Dietary daidzein influences laying performance of ducks (Anas platyrhynchos) and early post-hatch growth of their hatchlings by modulating gene expression. Zhao, RQ,Wang, YJ,Zhou, YC,Ni, YD,Lu, LZ,Grossmann, R,Chen, J.

[11]High concentrations of genistein exhibit pro-oxidant effects in primary muscle cells through mechanisms involving 5-lipoxygenase-mediated production of reactive oxygen species. Lin, Ying Cai.

[12]Effects of soy isoflavone on performance, meat quality and antioxidative property of male broilers fed oxidized fish oil. Jiang, S. Q.,Jiang, Z. Y.,Lin, Y. C.,Xi, P. B.,Ma, X. Y.. 2007

[13]Antioxidant Effects of Oats Avenanthramides on Human Serum. Yang Nan,Hou Zhao-hua,Yao Yang,Zhou Xian-rong,Ren Gui-xing,Liu Sen,Lue Li. 2011

[14]Protective effect of Momordica charantia water extract against liver injury in restraint-stressed mice and the underlying mechanism. Deng, Yuanyuan,Tang, Qin,Zhang, Yan,Zhang, Ruifen,Wei, Zhencheng,Tang, Xiaojun,Zhang, Mingwei. 2017

[15]Effects of selenium source and level on growth performance, tissue selenium concentrations, antioxidation, and immune functions of heat-stressed broilers. Liao, Xiudong,Lu, Lin,Li, Sufen,Liu, Songbai,Zhang, Liyang,Luo, Xugang,Liao, Xiudong,Wang, Guangying,Li, Ang,Li, Sufen.

[16]The effect of equol injection in ovo on posthatch growth, meat quality and antioxidation in broilers. Wei, X. J.,Ni, Y. D.,Zhao, R. Q.,Lu, L. Z.,Grossmann, R.. 2011

[17]Proteomic Analysis of Cold Stress Responses in Banana Leaves. Feng, Ren-jun,Zhang, Li-li,Wang, Jing-yi,Luo, Jin-mei,Peng, Ming,Qi, Jun-feng,Zhang, Yin-don,Lu, Li-fang.

[18]Effects of flaxseed oil on anti-oxidative system and membrane deformation of human peripheral blood erythrocytes in high glucose level. Huang, Qingde,Xu, Jiqu,Deng, Qianchun,Huang, Fenghong,Yang, Wei,Fu, Juan,Yu, Miao,Wang, Di,Yao, Ping,Liu, Liegang,Yang, Wei,Fu, Juan,Yu, Miao,Wang, Di,Yao, Ping,Liu, Liegang. 2012

[19]Effects of High-Dose Daidzein on Laying Performance, Egg Quality and Anticoddation in Laying Hens. Cai, Juan,Shi, Shourong,Tong, Haibing,Gu, Huan. 2013

[20]Antioxidation Study of Pholiota adiposa (Fr.) Quel and Its Polysaccharides. Gong, Chunyu,Hu, Qingxiu,Ji, Yemei. 2012

作者其他论文 更多>>

微信小程序