Salidroside liposome formulation enhances the activity of dendritic cells and immune responses

文献类型: 外文期刊

第一作者: Zhao, Xiaojuan

作者: Zhao, Xiaojuan;Tao, Yang;Huang, Yee;Wang, Deyun;Hu, Yuanliang;Liu, Jiaguo;Wu, Yi;Yu, Yun;Liu, Cui;Zhao, Xiaojuan;Lu, Yu

作者机构:

关键词: Salidroside liposomes;Dendritic cells;OVA;Vaccine;Adjuvant

期刊名称:INTERNATIONAL IMMUNOPHARMACOLOGY ( 影响因子:4.932; 五年影响因子:4.624 )

ISSN: 1567-5769

年卷期: 2013 年 17 卷 4 期

页码:

收录情况: SCI

摘要: Salidroside, the important composition, of Rhodiola rosea L has been reported to have various pharmacological properties. Liposome is known to be effective as drug carriers and immune adjuvant Therefore, the aim of this study is to investigate immunological adjuvant activity of salidroside liposome. Here we reported the preparation, the effect on DCs in vitro and the immune response in vivo. The immunological adjuvant activity of salidroside liposome formulation was compared with that of salidroside and liposome. The result showed that salidroside liposome formulation not only could promote the maturation of DCs, the stimulation of DCs on MLR proliferation and the antigen presenting ability, but also induced the sustained cellular immune and humoral immune response. Overall, the results showed that salidroside liposome formulation had the potential to act as effective sustained release vaccine delivery systems. (C) 2013 Elsevier B.V. All rights reserved.

分类号:

  • 相关文献

[1]Dendritic cell targeted vaccines: Recent progresses and challenges. Chen, Pengfei,Liu, Xinsheng,Sun, Yuefeng,Zhou, Peng,Wang, Yonglu,Zhang, Yongguang.

[2]Enhancement of immune responses to Newcastle disease vaccine by a supplement of extract of Momordica cochinchinensis (Lour.) Spreng. seeds. Xiao, C.,Hu, S.,Xiao, C.,Bao, G.. 2009

[3]Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice. Gai, Weiwei,Zhang, Weijiao,Qiu, Boning,Gai, Weiwei,Wang, Hualei,Zhao, Yongkun,Wang, Qi,Zhang, Weijiao,Feng, Na,Qiu, Boning,Chi, Hang,Li, Nan,Wang, Tiecheng,Gao, Yuwei,Yang, Songtao,Xia, Xianzhu,Zheng, Xuexing,Wang, Chong,Wang, Qi,Wong, Gary,Shan, Junjie,Shan, Junjie,Yang, Songtao,Xia, Xianzhu. 2017

[4]Short communication. Enhancement of the immune responses to vaccination against foot-and-mouth disease in mice by oral administration of Quillaja saponaria-A and extracts of Cochinchina momordica seed. Xiao, C. W.,Bao, G.,Rajput, Z. I.,Hu, S. H.,Rajput, Z. I.,Soomro, N. A.. 2013

[5]A multivalent killed whole-cell vaccine induces effective protection against Edwardsiella tarda and Vibrio anguillarum. Sun, Yun,Sun, Li,Liu, Chun-sheng,Sun, Yun.

[6]Protecting Local Breeds of Livestock in NW China. Lang Xia,Wang Cailian,Squires, Victor. 2010

[7]Comparative study of the immune effect of an Edwardsiella tarda antigen in two forms: Subunit vaccine vs DNA vaccine. Sun, Yun,Sun, Li,Sun, Yun,Liu, Chun-Sheng.

[8]The immune mechanism of Mycoplasma hyopneumoniae 168 vaccine strain through dendritic cells. Shen, Yumeng,Hu, Weiwei,Yang, Qian,Wei, Yanna,Feng, Zhixin. 2017

[9]Approaches to improved targeting of DNA vaccines. Wang, Gang,Pan, Li,Zhang, Yongguang.

[10]Chlamydia abortus Pmp18.1 Induces IL-1 beta Secretion by TLR4 Activation through the MyD88, NF-kappa B, and Caspase-1 Signaling Pathways. Pan, Qing,Pais, Roshan,Eko, Francis O.,Pan, Qing,Zhang, Qiang,Chu, Jun,Liu, Shanshan,He, Cheng,Pan, Qing. 2017

[11]SjCRT, a recombinant Schistosoma japonicum calreticulin, induces maturation of dendritic cells and a Th1-polarized immune response in mice. Ma, Lizhen,Li, Dandan,Yuan, Chunxiu,Zhang, Xiangqian,Ta, Na,Zhao, Xiaochao,Li, Yumei,Feng, Xingang,Li, Dandan,Li, Yumei,Yuan, Chunxiu. 2017

[12]Infection of mouse bone marrow-derived immature dendritic cells with classical swine fever virus C-strain promotes cells maturation and lymphocyte proliferation. Zheng, Fu-Ying,Qiu, Chang-Qing,Jia, Huai-Jie,Chen, Guo-Hua,Zeng, Shuang,He, Xiao-Bing,Fang, Yong-Xiang,Lin, Guo-Zhen,Jing, Zhi-Zhong. 2013

[13]Effects of Mycoplasma hyopneumoniae on porcine nasal cavity dendritic cells. Shen, Yumeng,Hu, Weiwei,Yang, Qian,Wei, Yanna,Feng, Zhixin.

[14]Newcastle disease virus-like particles induce DC maturation through TLR4/NF-kappa B pathway and facilitate DC migration by CCR7-CCL19/CCL21 axis. Qian, Jing,Xu, Xiaohong,Ding, Jiaxin,Yin, Renfu,Xue, Cong,Cong, Yanlong,Ding, Zhuang,Sun, Yixue,Wang, Jianzhong,Wang, Chunfeng,Ding, Chan,Yu, Shengqing,Liu, Xiufan,Hu, Shunlin.

[15]An inactivated gE-deleted pseudorabies vaccine provides complete clinical protection and reduces virus shedding against challenge by a Chinese pseudorabies variant. Wang, Jichun,Guo, Rongli,Qiao, Yongfeng,Xu, Mengwei,Wang, Zhisheng,Liu, Yamei,Gu, Yiqi,Liu, Chang,Hou, Jibo,Gu, Yiqi,Liu, Chang,Wang, Jichun,Guo, Rongli,Qiao, Yongfeng,Xu, Mengwei,Wang, Zhisheng,Liu, Yamei,Hou, Jibo. 2016

[16]CTA1: Purified and display onto gram-positive enhancer matrix (GEM) particles as mucosal adjuvant. Zhang, Yuanpeng,Yu, Xiaoming,Hou, Liting,Chen, Jin,Li, Pengcheng,Qiao, Xuwen,Zheng, Qisheng,Hou, Jibo,Zhang, Yuanpeng,Yu, Xiaoming,Hou, Liting,Chen, Jin,Li, Pengcheng,Qiao, Xuwen,Zheng, Qisheng,Hou, Jibo,Zhang, Yuanpeng,Yu, Xiaoming,Hou, Liting,Chen, Jin,Li, Pengcheng,Qiao, Xuwen,Zheng, Qisheng,Hou, Jibo. 2018

[17]Effects of different cytokines on immune responses of rainbow trout in a virus DNA vaccination model. Cao, Yongsheng,Xu, Liming,Li, Shaowu,Wang, Di,Zhao, Jingzhuang,Liu, Hongbai,Lu, Tongyan,Cao, Yongsheng,Zhang, Qiya,Feng, Jian. 2017

[18]Adjuvant Effect of Quillaja saponaria Saponin (QSS) on Protective Efficacy and IgM Generation in Turbot (Scophthalmus maximus) upon Immersion Vaccination. Wang, Yujuan,Wang, Xiuhua,Huang, Jie,Wang, Xiuhua,Huang, Jie,Li, Jun,Li, Jun,Li, Jun. 2016

[19]Lycium barbarum polysaccharides as an adjuvant for recombinant vaccine through enhancement of humoral immunity by activating Tfh cells. Su, Chun-xia,Feng-Wang,Zheng, Jie,Ling-Huang,Wang, Ning-ping,Duan, Xiang-guo,Duan, Xiang-guo,Duan, Xiang-guo,Liang, Li-jun,Fu, Xue-Yan,Yan, Ya-mei. 2014

[20]Characterization of droplet impact and deposit formation on leaf surfaces. Dong, Xiang,Yang, Xuejun,Zhu, Heping.

作者其他论文 更多>>