The prevalent status and genetic diversity of porcine reproductive and respiratory syndrome virus in China: a molecular epidemiological perspective

文献类型： 外文期刊

第一作者： Guo, Zhenhua

作者： Guo, Zhenhua;Chen, Xin-xin;Li, Rui;Qiao, Songlin;Zhang, Gaiping;Zhang, Gaiping;Zhang, Gaiping

作者机构：

关键词： Porcine reproductive and respiratory syndrome virus (PRRSV);Molecular epidemiology;PRRSV-1;PRRSV-2;Control strategies

期刊名称：VIROLOGY JOURNAL （ 影响因子：4.099； 五年影响因子：3.719 ）

ISSN： 1743-422X

年卷期： 2018 年 15 卷

页码：

收录情况： SCI

摘要： Porcine reproductive and respiratory syndrome virus (PRRSV) has been epidemic more than 30 years in America and 20 years in China. It is still one of the most important causative agents to the worldwide swine industry. Here, we systematically analyzed the prevalence status of PRRSV in China by a molecular epidemiological perspective. Now both PRRSV-1 and PRRSV-2 are circulating and approximately more than 80% of pig farms are seropositive for PRRSV. For PRRSV-2, there are four lineages (lineage 1, lineage 3, lineage 5, lineage 8) circulating in the fields. Lineage 8 (CH-1a-like) and lineage 5 (BJ-4-like) appeared almost at the same time during 1995-1996. Notably, BJ-4 shares 99.6% and 99.8% identity with VR2332 and RespPRRS MLV, respectively. It means that lineage 5 is likely to be imported from America. Now highly pathogenic PRRSV (HP-PRRSV) which was considered to be evolved from local diversity of lineage 8 strains is predominant with different variants. Lineage 3 appeared in 2010 which is mainly sporadic in south of China. Lineage 1, also known as NADC30-like strains in China, has been prevalent since 2013 and leads to PRRS pandemic again. For PRRSV-1, although sporadic at present, more than 9 provinces/regions have been reported. All the circulating strains belong to subtype I. It should be paid more attention since there are no vaccines available. Our analysis would help to deeply understand the prevalent status of PRRSV in China and provide useful information for prevention and control of porcine reproductive and respiratory syndrome (PRRS).

分类号：

  • 相关文献

[1]Risk Evaluation of Main Pests and Integrated Management in Chinese Wolfberry, Lycium barbarum L.. Yu, Mingfu,Zhu, Fengyun,Ali, Abid,Kidane, Dawit,Kidane, Dawit. 2015

[2]Molecular epidemiology of hydropericardium syndrome outbreak-associated serotype 4 fowl adenovirus isolates in central China. Zhang, Teng,Zhang, Teng,Jin, Qianyue,Ding, Peiyang,Chai, Yongxiao,Li, Yafei,Liu, Xiao,Luo, Jun,Zhang, Gaiping,Chai, Yongxiao,Liu, Xiao,Zhang, Gaiping,Ding, Peiyang,Li, Yafei,Wang, Yinbiao,Jin, Qianyue,Zhang, Gaiping. 2016

[3]The detection of porcine circovirus 3 in Guangxi, China. Wen, S.,Sun, W.,Li, Z.,Zhuang, X.,Zhao, G.,Xie, C.,Jing, J.,Xiao, P.,Wang, M.,Han, J.,Lu, H.,Jin, N.,Sun, W.,Wang, M.,Li, Z.,Zhao, G.,Zheng, M.,Ren, J.,Liu, H.. 2018

[4]Detection of Latent Infection of Wheat Leaves Caused by Blumeria graminis f.sp tritici Using Nested PCR. . 2010

[5]Porcine reproductive and respiratory syndrome virus attachment is mediated by the N-terminal domain of the sialoadhesin receptor. Tong, Guang-Zhi,An, Tong-Qing,Tian, Zhi-Jun,He, Yun-Xia,Xiao, Yan,Jiang, Yi-Feng,Peng, Jin-Mei,Zhou, Yan-Jun,Tong, Guang-Zhi,An, Tong-Qing,Liu, Di.

[6]Real-time PCR quantification of latent infection of wheat powdery mildew in the field. Zhou, Yilin,Zeng, Xiaowei,Duan, Xiayu,Cao, Xueren,Luo, Yong,Song, Yuli,Wang, Baotong.

[7]Molecular epidemiological and phylogenetic analyses of canine parvovirus in domestic dogs and cats in Beijing, 2010-2013. Wu, Jing,Gao, Xin-Tao,Hou, Shao-Hua,Guo, Xiao-Yu,Yuan, Wei-Feng,Xin, Ting,Zhu, Hong-Pei,Jia, Hong,Yang, Xue-Shong.

[8]Amino acid at position 176 was essential for porcine reproductive and respiratory syndrome virus (PRRSV) non-structural protein 1 alpha (nsp1 alpha) as an inhibitor to the induction of IFN-beta. Shi, Xibao,Chen, Jing,Xing, Guangxu,Zhang, Gaiping,Shi, Xibao,Chen, Jing,Xing, Guangxu,Hu, Xiaofei,Zhi, Yubao,Guo, Junqing,Wang, Li,Qiao, Songlin,Lu, Qingxia,Zhang, Gaiping,Zhang, Xiaozhuan.

[9]Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Inhibits RNA-Mediated Gene Silencing by Targeting Ago-2. Chen, Jing,Zhang, Gaiping,Chen, Jing,Shi, Xibao,Wang, Li,Luo, Jun,Xing, Guangxu,Deng, Ruiguang,Zhang, Gaiping,Shi, Xibao,Zhang, Xiaozhuan,Yang, Hong,Li, Jinting,Wang, Aiping,Zhang, Gaiping. 2015

[10]Identification and characterization of a novel subgenotype of bovine viral diarrhea virus isolated from dairy cattle in Northwestern China. Gong, Xiaowei,Cao, Xiaoan,Zheng, Fuying,Chen, Qiwei,Zhou, Jizhang,Yin, Hong,Cai, Xuepeng,Liu, Lihong. 2013

[11]Molecular epidemiological investigation of porcine reproductive and respiratory syndrome virus in Northwest China from 2007 to 2010. Shang, Youjun,Wang, Guangxiang,Tian, Hong,Yin, Shuanghui,Du, Ping,Wu, Jinyan,Chen, Yan,Yang, Shunli,Jin, Ye,Zhang, Keshan,Liu, Xiangtao.

[12]Common occurrence of a unique Cryptosporidium ryanae variant in zebu cattle and water buffaloes in the buffer zone of the Chitwan National Park, Nepal. Dearen, Theresa K.,Xiao, Lihua,Feng, Yaoyu,Feng, Yaoyu,Karna, Sandeep Raj,Singh, Dinesh Kumar,Adhikari, Lekh Nath,Shrestha, Aruna.

[13]Molecular epidemiology of Aleutian mink disease virus in China. Wang, Zhenjun,Wu, Wei,Hu, Bo,Zhang, Hailing,Bai, Xue,Zhao, Jianjun,Zhang, Lei,Yan, Xijun.

[14]Porcine reproductive and respiratory syndrome virus (PRRSV) could be sensed by professional beta interferon-producing system and had mechanisms to inhibit this action in MARC-145 cells. Shi, Xibao,Wang, Li,Zhi, Yubao,Xing, Guangxu,Zhao, Dong,Deng, Ruiguang,Zhang, Gaiping. 2010

[15]Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-beta induction. Shi, Xibao,Wang, Li,Li, Xuewu,Zhang, Gaiping,Guo, Junqing,Zhao, Dong,Chai, Shujun,Deng, Ruiguang. 2011

[16]Downregulation of protein kinase PKR activation by porcine reproductive and respiratory syndrome virus at its early stage infection. Xiao, Yueqiang,Ma, Zexu,Wang, Rong,Yang, Liping,Nan, Yuchen,Zhang, Yan-Jin,Xiao, Yueqiang,Ma, Zexu,Wang, Rong,Yang, Liping,Nan, Yuchen,Zhang, Yan-Jin,Xiao, Yueqiang.

[17]Antibody-dependent enhancement of PRRSV infection down-modulates TNF-alpha and IFN-beta transcription in macrophages. Bao, Dengke,Wan, Bo,Wang, Yinbiao,Zhang, Gaiping,Bao, Dengke,Wang, Rui,Qiao, Songlin,Wan, Bo,Wang, Yinbiao,Liu, Mingyang,Shi, Xibao,Guo, Juiqing,Zhang, Gaiping.

[18]Emerging and endemic types of Ostreid herpesvirus 1 were detected in bivalves in China. Bai, Changming,Wang, Chongming,Xia, Junyang,Zhang, Shuai,Huang, Jie,Bai, Changming,Wang, Chongming,Huang, Jie,Sun, Hailin.

[19]A multiplex PCR for rapid and simultaneous detection of porcine circovirus type 2, porcine parvovirus, porcine pseudorabies virus, and porcine reproductive and respiratory syndrome virus in clinical specimens. Yue, Fengxiong,Cui, Shangjin,Zhang, Chaofan,Yoon, Kyoung-Jin. 2009

[20]Immune responses of swine following DNA immunization with plasmids encoding porcine reproductive and respiratory syndrome virus ORFs 5 and 7, and porcine IL-2 and IFN gamma. Xue, QN,Zhao, YG,Zhou, YJ,Qiu, HJ,Wang, YF,Wu, DL,Tian, ZJ,Tong, GZ. 2004

作者其他论文 更多>>

微信小程序