Toxicological analysis of triadimefon on endocrine disruption and oxidative stress during rare minnow (Gobiocypris rarus) larvae development
文献类型: 外文期刊
第一作者: Jiang, Jinhua
作者: Jiang, Jinhua;Hu, Gaojie;Zhang, Changpeng;Zhao, Xueping;Wang, Qiang;Chen, Liezhong
作者机构:
关键词: Triadimefon;Endocrine disruption;Oxidative stress;Gobiocypris rarus;larvae
期刊名称:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH ( 影响因子:4.223; 五年影响因子:4.306 )
ISSN: 0944-1344
年卷期: 2017 年 24 卷 34 期
页码:
收录情况: SCI
摘要: Triadimefon (TDF) is a systemic wide-spectrum antifungal compound that is widely used in agriculture to inhibit fungal growth on various crops. Since previous studies focused on the embryo and adult life stages in the investigation of ecological impact, here we investigated the long-term effects of TDF (1, 10, 100 mu g/L) on rare minnow during its larvae development. TDF caused an anti-estrogenic effect by decreasing vitellogenin (VTG) and CYP19a mRNA level, and inhibiting the aromatase activity and VTG levels after a 3, 6, 10, or 14-day exposure in rare minnow larvae. TDF also disturbed the endocrine disruption by regulating the transcription of estrogen receptors ER alpha, ER beta 1 and ER beta 2, CYP1a, CYP11, CYP17, steroidogenic acute regulator (STAR), doublesex and mab-3 related transcription factor (DMRT1), gonadotropin-releasing hormone (GnRH2), GnRH3, GnRHR1A, and GnRHR1B. Furthermore, TDF induced the accumulation of reactive oxygen species (ROS) and the activity of antioxidant proteins glutathione peroxidase (GPX), superoxide dismutase (SOD), and catalase (CAT), and significantly increased the transcriptions of stress response genes P53, growth arrest and DNA damage-inducible 45 alpha (Gadd45 alpha), and COX1, suggested that TDF might cause oxidative stress during larvae development. The changes in transcript and biological levels represented the potential adaptive or compensatory responses to impaired oxidative stress and endocrine system after TDF exposure in rare minnow during its larvae development.
分类号:
- 相关文献
作者其他论文 更多>>
-
Carbon-14 labeled transformation of atrazine in soils: Comparison of superabsorbent hydrogel coating and technical material
作者:Cheng, Xi;Zhang, Chunrong;Tang, Tao;Zhao, Xueping;Ye, Qingfu;Yang, Jingying
关键词:Superabsorbent hydrogel; Atrazine; Soil; Fate model; Degradation
-
Freeze-thaw stability of Pickering emulsion stabilized by modified soy protein particles and its application in plant-based ice cream
作者:Hei, Xue;Liu, Zhe;Li, Shanshan;Wu, Chao;Jiao, Bo;Hu, Hui;Ma, Xiaojie;Zhu, Jinjin;Wang, Qiang;Shi, Aimin;Adhikari, Benu
关键词:Pickering emulsion; Freeze -thaw stability; Plant -based ice cream
-
Current-use pesticides monitoring and ecological risk assessment in vegetable soils at the provincial scale
作者:Zuo, Wei;Zhao, Yang;Qi, Peipei;Zhang, Chunrong;Zhao, Xueping;Wu, Shenggan;An, Xuehua;Liu, Xinju;Cheng, Xi;Tang, Tao;Yu, Yijun
关键词:Soil; Pesticide residue; Spatial distribution; Vegetable type; Ecological risk assessment
-
Long-term biogas slurry application increases microbial necromass but not plant lignin contribution to soil organic carbon in paddy soils as regulated by fungal community
作者:Chen, Zhaoming;Ma, Jinchuan;Ma, Junwei;Ye, Jing;Yu, Qiaogang;Zou, Ping;Sun, Wanchun;Lin, Hui;Wang, Feng;Wang, Qiang;Zhao, Xinlin
关键词:Soil organic carbon; Lignin phenols; Microbial necromass; Microbial community structure; Biogas slurry
-
Residue analysis and dietary risk assessment of picoxystrobin in potato (Solanum tuberosum), citrus fruit (Citrus reticulata Blanco), and Dendrobium officinale Kimura et Migo
作者:Dou, Wen;Chen, Yuting;Cheng, Youpu;Dou, Wen;Chen, Yuting;Ye, Hui;Fang, Nan;Luo, Yuqin;Wang, Xiangyun;Li, Yanjie;He, Hongmei;Zhang, Changpeng
关键词:Picoxystrobin; residue; dietary risk assessment; potato; citrus fruit; dendrobium officinale
-
A novel strain Lactiplantibacillus plantarum LPP95 isolated from Chinese pickles: Antifungal effect, mechanism, and potential application in yogurt
作者:Wang, Qiang;Zhang, Yu;Wang, Hongwei;Song, Jiajia;Suo, Huayi;Wang, Qiang;Zhang, Yu;Wang, Hongwei;Song, Jiajia;Suo, Huayi;Zhang, Feng;Zhang, Yuhong;Suo, Huayi
关键词:Antifungal activity; Lactiplantibacillus plantarum; Penicillium sp.; Antifungal substance; Yogurt
-
Long-term successive biochar application increases plant lignin and microbial necromass accumulation but decreases their contributions to soil organic carbon in rice-wheat cropping system
作者:Chen, Zhaoming;He, Lili;Ma, Jinchuan;Ma, Junwei;Ye, Jing;Yu, Qiaogang;Zou, Ping;Sun, Wanchun;Lin, Hui;Wang, Feng;Wang, Qiang;Zhao, Xu
关键词:amino sugars; biochar; lignin phenols; microbial necromass; paddy field; soil organic carbon