Meta-analysis of the association between PADI4-92C/G polymorphism and rheumatoid arthritis in the Chinese population

文献类型： 外文期刊

第一作者： Guo, Z. Y.

作者： Guo, Z. Y.;Lin, X. J.;Guo, Z. Y.;Mei, Y. F.;Zhang, J. X.;Wu, M.;Bu, C.;Xie, Y.;Wang, J.

作者机构：

关键词： Meta-analysis;Peptidylarginine deiminase 4;Polymorphism;Rheumatoid arthritis

期刊名称：BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH （ 影响因子：2.59； 五年影响因子：2.523 ）

ISSN： 0100-879X

年卷期： 2017 年 50 卷 10 期

页码：

收录情况： SCI

摘要： Many studies have evaluated the correlation between peptidylarginine deiminase 4 (PADI4) -92C/G polymorphism and rheumatoid arthritis (RA), but the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between PADI4 -92C/G polymorphism and RA. Eligible studies published before May 2016 were identified in PubMed and Chinese databases. The strengths of these associations were assessed by pooled odds ratios (OR) and 95% confidence interval (CI). Eight studies documenting a total of 1351 RA cases and 1585 controls were included in this meta-analysis. In the overall analysis, a significant association between the PADI4 -92C/G polymorphism and RA was found in the Chinese population (G vs C: OR=1.32, 95% CI=1.02-1.71; GG+ CG vs CC: OR=1.75, 95% CI=1.20-2.53). The subgroup analyses stratified by geographic area(s) and source of controls revealed significant results in South China, in hospital-based studies and population-based studies. In summary, this meta-analysis suggested that PADI4 -92C/G polymorphism may be associated with the RA incidence in the Chinese population, especially for South China. Further studies conducted on other ethnic groups are required for definite conclusions.

分类号：

  • 相关文献

[1]Synergistic effects of interleukin-1 beta, and interleukin-17A antibodies on collagen-induced arthritis mouse model. Zhang, Yu,Ren, Guiping,Guo, Mo,Ye, Xianlong,Zhao, Jingzhuang,Qi, Jianying,Kan, Fangming,Liu, Miao,Li, Deshan,Xu, Liming. 2013

[2]Expression of Programmed Death-1 (PD-1) on CD4+and CD8+T cells in Rheumatoid Arthritis. Li, Shufeng,Chen, Meng,Shan, Shiying,Yuan, Zhen,Liao, Wensheng,Song, Yuanlin,Zhang, Shuzhen,Song, Haihan. 2014

[3]Bi-specific antibodies with high antigen-binding affinity identified by flow cytometry. Xu, Liming,Zhao, Jingzhuang,Liu, Miao,Zhang, Yu,Wang, Qiuying,Guo, Mo,Li, Qingcui,Ren, Guiping,Li, Deshan,Jiang, Yuanyuan,Cao, Hongwei. 2015

[4]Fibroblast growth factor 21 (FGF21) ameliorates collagen-induced arthritis through modulating oxidative stress and suppressing nuclear factor-kappa B pathway. Yu, Yinhang,Li, Siming,Liu, Yaonan,Tian, Guiyou,Yuan, Qingyan,Bai, Fuliang,Wang, Wenfei,Ren, Guiping,Li, Deshan,Wang, Wenfei,Ren, Guiping,Li, Deshan,Zhang, Yu,Zhang, Zhiyi,Li, Siming. 2015

[5]Expression of TIM-3 on CD4+ and CD8+ T cells in the peripheral blood and synovial fluid of rheumatoid arthritis. Li, Shufeng,Peng, Dayong,He, Yeteng,Zhang, Hu,Sun, Huaqiang,Shan, Shiying,Zhang, Ming,Song, Yuanlin,Zhang, Shuzhen,Xiao, Hong,Song, Haihan.

[6]Earthworms affect plant growth and resistance against herbivores: A meta-analysis. Liu, Manqiang,Hu, Feng,Xiao, Zhenggao,Kergunteuil, Alan,Le Bayon, Renee-Claire,Rasmann, Sergio,Wang, Xie,Koricheva, Julia,Liu, Manqiang,Hu, Feng. 2018

[7]Effect of Diacylglycerol Supplementation on Fasting Serum Triacylglycerol Concentration: a Meta-Analysis. Wang, Wenliang,Xu, Tongcheng,Zhu, Qingjun,Cheng, Anwei,Du, Fangling,Xu, Tongcheng,Li, Duo,Li, Xia. 2010

[8]Effect of Diacylglycerol on Postprandial Serum Triacylglycerol Concentration: A Meta-analysis. Xu, Tongcheng,Zhang, Zhiguo,Li, Duo,Li, Xia,Xu, Tongcheng,Ma, Xiaohang,Zhang, Tiansong. 2009

[9]Systematic review and meta-analysis of soy products consumption in patients with type 2 diabetes mellitus. Yang, Bin,Chen, Ying,Xu, Tongchen,Yu, Yinghua,Huang, Tao,Hu, Xiaojie,Li, Duo,Xu, Tongchen,Yu, Yinghua. 2011

[10]Effect of diacylglycerol on body weight: a meta-analysis. Xu, Tongcheng,Zhang, Zhiguo,Li, Duo,Xu, Tongcheng,Li, Xia,Ma, Xiaohang. 2008

[11]Meta-analysis of constitutive QTLs for disease resistance in maize and its synteny conservation in the rice genome. Zhao, L.,Wang, Q. Y.,Liu, H. J.,Zhang, C. X.,Li, X. H.. 2015

[12]The characteristics of yield-scaled methane emission from paddy field in recent 35-year in China: A meta-analysis. Guo, Jia,Zhu, Yaojun,Wei, Wei,Li, Shengnan,Yu, Yilei,Guo, Jia,Zhu, Yaojun,Wei, Wei,Li, Shengnan,Yu, Yilei,Song, Zhifeng. 2017

[13]Association between genetic polymorphisms of antioxidant enzyme genes and susceptibility to hepatocellular carcinoma: a meta-analysis. Meng, Zhaolu,Shi, Huiling. 2016

[14]Higher yields and lower methane emissions with new rice cultivars. Hu, Shuijin,Yan, Xiaojun,Wang, Lili,Zhang, Yi,Zhang, Weijian,Jiang, Yu,Zhang, Jun,Song, Zhenwei,Zheng, Chengyan,Deng, Aixing,Zhang, Weijian,van Groenigen, Kees Jan,van Groenigen, Kees Jan,van Kessel, Chris,Linquist, Bruce A.,Huang, Shan,Hungate, Bruce A.,Hu, Shuijin,Wu, Lianhai,Chen, Jin,Hang, Xiaoning,Horwath, William R.,Ye, Rongzhong.

[15]Combining QTL and candidate gene analysis with phenotypic model to unravel the relationship between lodging and related traits in soybean. Chen, Haifeng,Yang, Zhonglu,Chen, Limiao,Zhang, Chanjuan,Yuan, Songli,Zhang, Xiaojuan,Qiu, Dezhen,Wan, Qiao,Chen, Shuilian,Shan, Zhihui,Zhou, Xinan,Zhan, Yong.

[16]Increased salt tolerance with overexpression of cation/proton antiporter 1 genes: a meta-analysis. Ma, Yuan-Chun,Ma, Yuan-Chun,Dong, Chao,Cheng, Zong-Ming (Max),Ma, Yuan-Chun,Auge, Robert M.,Cheng, Zong-Ming (Max). 2017

[17]Does Bt rice pose risks to non-target arthropods? Results of a meta-analysis in China. Lu, Zengbin,Wang, Long,Chang, Xuefei,Wang, Fang,Yao, Hongwei,Ye, Gongyin,Dang, Cong,Lu, Zengbin,Wang, Long,Chang, Xuefei,Wang, Fang,Yao, Hongwei,Ye, Gongyin,Lu, Zengbin,Peng, Yufa,Stanley, David.

[18]The effect of no-till on organic C storage in Chinese soils should not be overemphasized: A meta-analysis. Du, Zhangliu,Zhang, Qingzhong,Li, Guichun,Angers, Denis A.,Ren, Tusheng.

[19]Genetic analysis of Verticillium wilt resistance in a backcross inbred line population and a meta-analysis of quantitative trait loci for disease resistance in cotton. Jinfa Zhang,Jiwen Yu,Wenfeng Pei,Xingli Li,Joseph Said,Mingzhou Song,Soum Sanogo. 2015

[20]From meta-studies to modeling: Using synthesis knowledge to build broadly applicable process-based land change models. Magliocca, Nicholas R.,van Vliet, Jasper,Ornetsmuller, Christine,Verburg, Peter H.,Brown, Calum,Evans, Tom P.,Evans, Tom P.,Houet, Thomas,Messerli, Peter,Messina, Joseph P.,Messina, Joseph P.,Nicholas, Kimberly A.,Sagebiel, Julian,Sagebiel, Julian,Schweizer, Vanessa,Yu, Qiangyi. 2015

作者其他论文 更多>>

微信小程序