Expression pattern of adipocyte fatty acid-binding protein gene in different tissues and its regulation of genes related to adipocyte differentiation in duck

文献类型: 外文期刊

第一作者: He, J.

作者: He, J.;Tian, Y.;Li, J. J.;Shen, J. D.;Tao, Z. R.;Lu, L. Z.;He, J.;Fu, Y.;Niu, D.;Lu, L. Z.

作者机构:

关键词: adipocyte fatty acid-binding protein;small interfering RNA;gene expression;regulation;duck

期刊名称:POULTRY SCIENCE ( 影响因子:3.352; 五年影响因子:3.679 )

ISSN: 0032-5791

年卷期: 2012 年 91 卷 9 期

页码:

收录情况: SCI

摘要: Abundance of duck adipocyte fatty acid-binding protein (A-FABP) mRNA was detected in this study by quantitative real-time PCR. The results showed that duck A-FABP gene was expressed in muscular tissues and many organs, except pancreas, lung, and kidney, and highly expressed in adipose tissues, especially in sebum. The expression of A-FABP and adipocyte differentiation-related genes was upregulated by oleic acid, and the A-FABP knockdown suppressed the oleic acid-stimulated expression of these genes in the cultured duck adipocytes, indicating A-FABP might play an important role in duck adipocyte differentiation.

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