The novel MGC13096 protein is correlated with proliferation

文献类型： 外文期刊

第一作者： Chen, Qiu

作者： Chen, Qiu;Yan, Qingfeng;Feng, Lifeng;Qian, Kaixian;Yan, Chengqi;Chen, Jianping;Chen, Qiu

作者机构：

关键词： MGC13096;proliferation

期刊名称：CELL BIOCHEMISTRY AND FUNCTION （ 影响因子：3.685； 五年影响因子：3.133 ）

ISSN： 0263-6484

年卷期： 2008 年 26 卷 2 期

页码：

收录情况： SCI

摘要： We report a functional characterisation of the novel protein MGC 13096. MGC 13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC 13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1), cAMP response element binding protein (CREB), nuclear factor of activated T cells (NFAT), NF-kappa B, signal transducer and activator of transcription 1 (STAT1) took part in the process. Copyright (c) 2007 John Wiley & Sons, Ltd.

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