The inhibiting activity of areca inflorescence extracts on human low density lipoprotein oxidation induced by cupric ion

文献类型: 外文期刊

第一作者: Chen, Weijun

作者: Chen, Weijun;Zhang, Chunmei;Huang, Yulin;Cheng, Fangfang;Shen, Yan;Tang, Minmin;Zheng, Yajun;Zhao, Songlin;Chen, Weijun;Wang, Rencai;Zhang, Chunmei;Zhao, Songlin

作者机构:

关键词: lipid peroxidation;human LDL;areca inflorescence extracts;cupric ion

期刊名称:INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION ( 影响因子:3.833; 五年影响因子:3.859 )

ISSN: 0963-7486

年卷期: 2012 年 63 卷 2 期

页码:

收录情况: SCI

摘要: The oxidative modification of human low density lipoprotein (LDL) plays a significant role in atherosclerosis. In this study, the inhibiting activity of areca inflorescence extracts (AIEs) on LDL oxidation was investigated by an in vitro study with Trolox as the standard antioxidant. The kinetics of LDL oxidation, thiobarbituric acid reactive substances assay, ferric-reducing antioxidant power assay and copper chelation assay were also evaluated to assess the antioxidant activities of AIEs, and the results revealed that AIEs could delay the lag time and inhibit the formation of malondialdehyde in the process of LDL peroxidation induced by Cu2+. The boiled water extract displayed the highest antioxidant activity compared with the ambient water extract and ethanol extract. The total phenolic contents and phenolic components of AIEs were also measured by high performance liquid chromatography method. Epicatechin, gallic acid and coumalic acid were the primary phenolic acids in AIEs.

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