Cytotoxic Cardenolide Glycosides from the Seeds of Antiaris toxicaria

文献类型： 外文期刊

第一作者： Dong, Wen-Hua

作者： Dong, Wen-Hua;Mei, Wen-Li;Zhao, You-Xing;Zeng, Yan-Bo;Zuo, Wen-Jian;Wang, Hui;Li, Xiao-Na;Dai, Hao-Fu

作者机构：

关键词： Antiaris toxicaria;Moraceae;cardenolides;SGC-7901;SMMC-7721

期刊名称：PLANTA MEDICA （ 影响因子：3.352； 五年影响因子：3.4 ）

ISSN： 0032-0943

年卷期： 2011 年 77 卷 15 期

页码：

收录情况： SCI

摘要： Bioassay-guided fractionation of the ethanolic extract from the seeds of Antiaris toxicaria led to the isolation of three new cardiac glycosides named toxicarioside J (1), toxicarioside K (2), and toxicarioside L (3), together with a known glucostrophalloside (4). The structures of the new compounds were elucidated by spectroscopic methods including HRESIMS, UV, IR, and 1D, 2D NMR techniques. The cytotoxic activities of these cardiac glycosides against human gastric (SGC-7901) and human hepatoma (SMMC-7721) cell lines were evaluated, and all of them exhibited significant cytotoxicity.

分类号：

  • 相关文献

[1]A new cytotoxic cardenolide from the latex of Antiaris toxicaria. Gan, Yu Juan,Mei, Wen Li,Dai, Hao Fu,Zhao, You Xing. 2009

[2]Two new epimeric pairs of iridoid from mangrove plant Scyphiphora hydrophyllacea. Zeng, Yan Bo,Mei, Wen Li,Zhuang, Ling,Hong, Kui,Dai, Hao Fu,Zhao, You Xing.

[3]Two 2-phenylbenzofuran derivatives from Morus atropurpurea. Wang, Wen-Jing,Wu, Dong-Ling,Fan, Chun-Lin,Li, Guo-Qiang,Wang, Ying,Zhang, Xiao-Qi,Ye, Wen-Cai,Liao, Sen-Tai,Zhang, Xian-Tao.

[4]A new drimane sesquiterpenoid glycoside from the seeds of Antiaris toxicaria. Dong, Wen-Hua,Mei, Wen-Li,Zhao, You-Xing,Zeng, Yan-Bo,Wang, Hui,Dai, Hao-Fu,Dong, Wen-Hua,Mei, Wen-Li,Zhao, You-Xing,Zeng, Yan-Bo,Wang, Hui,Dai, Hao-Fu. 2011

[5]Study on the Chemical Constituents from the Latex of Antiaris toxicaria. Mei Wenli,Gan Yujuan,Que Dongmei,Li Xiaona,Dai Haofu. 2011

[6]Structure Elucidation of Flavonoids from Antiaris toxicaria Roots. Que Dongmei,Mei Wenli,Wu Jiao,Han Zhuang,Dai Haofu. 2009

[7]Two new cytotoxic cardenolides from the latex of Antiaris toxicaria. Dai, Hao-Fu,Gan, Yu-Juan,Que, Dong-Mei,Wu, Jiao,Mei, Wen-Li,Wen, Zhen-Chang. 2009

[8]A New Cytotoxic 19-Nor-cardenolide from the Latex of Antiaris toxicaria. Dai, Hao-Fu,Gan, Yu-Juan,Que, Dong-Mei,Wu, Jiao,Mei, Wen-Li,Wen, Zhen-Chang. 2009

[9]Two new strophanthidol cardenolides from the seeds of Antiaris toxicaria. Zuo, Wen-Jian,Dong, Wen-Hua,Zhao, You-Xing,Chen, Hui-Qin,Mei, Wen-Li,Dai, Hao-Fu,Jing-Chen.

作者其他论文 更多>>

微信小程序