4 beta-Isocyanopodophyllotoxins: valuable precursors for the synthesis of new podophyllotoxin analogues

文献类型: 外文期刊

第一作者: Liu, Ying-Qian

作者: Liu, Ying-Qian;Li, Lin-Hai;Li, Wen-Qun;Feng, Gang;Yang, Liu

作者机构:

关键词: 4 beta-isocyanopodophyllotoxins;anticancer drugs;multicomponent reactions;ultrasound

期刊名称:CHEMICAL PAPERS ( 影响因子:2.097; 五年影响因子:1.831 )

ISSN: 0366-6352

年卷期: 2011 年 65 卷 5 期

页码:

收录情况: SCI

摘要: A new and efficient method for the synthesis of novel 4 beta-isocyanopodophyllotoxins as a valuable building block for the synthesis of versatile bioactive podophyllotoxin analogues under both classical and ultrasonic conditions was developed. In general, significant improvements in rates of reaction and yields of sonochemical reactions relative to the classical ones were observed.

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