Formulation of vanillin cross-linked chitosan nanoparticles and its characterization
文献类型: 外文期刊
第一作者: Wang, Guang
作者: Wang, Guang;Li, Puwang;Peng, Zheng;Huang, Maofang;Kong, Lingxue
作者机构:
关键词: Chitosan;Vanillin;Nanoparticles;Cross-linker
期刊名称:ADVANCED MATERIALS AND STRUCTURES, PTS 1 AND 2
ISSN: 1022-6680
年卷期: 2011 年 335-336 卷
页码:
收录情况: SCI
摘要: Chitosan nanoparticles were successfully prepared by chemical cross-linking with vanillin. The nanoparticles were spherical in shape with smooth surface, and the average particle size of chitosan nanoparticles was 141 nm. The formulation of chitosan nanoparticles is based on Shiff reaction between aldehyde group of vanillin and amino group of chitosan. Chitosan nanoparticles prepared by crosslinking with vanillin are promising vehicle for the drug delivery of various anticancer drugs in the chemotherapy of cancers.
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