A new cytotoxic 2-(2-phenylethyl)chromone from Chinese eaglewood

文献类型： 外文期刊

第一作者： Liu, Jun

作者： Liu, Jun;Wu, Jiao;Deng, Yuan Yuan;Mei, Wen Li;Dai, Hao Fu;Zhao, You Xing

作者机构：

关键词： Chinese eaglewood;Aquilaria sinensis;Chromone;Cytotoxicity

期刊名称：CHINESE CHEMICAL LETTERS （ 影响因子：6.779； 五年影响因子：4.558 ）

ISSN： 1001-8417

年卷期： 2008 年 19 卷 8 期

页码：

收录情况： SCI

摘要： A new compound 8-chloro-5,6,7-trihydroxy-2-(3-hydroxy-4-methoxyphenethyl)-5,6,7,8-tetrahydro-4H-chromen-4-one (1) was isolated from the Chinese eaglewood [Aquilaria sinensis (Lour.) Gilg]. Its structure was elucidated on the basis of spectral data. Compound 1 showed cytotoxicity against human gastric cancer cell line (SGC-7901) in vitro by MTT method with the IC(50) value of 14.6 mu g/mL. (C) 2008 Wen Li Mei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

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