Self-assembled nanosensor based on squaraine dye for specific recognition and detection of human serum albumin

文献类型： 外文期刊

第一作者： Guo, Yanyan

作者： Guo, Yanyan;Chen, Yiping;Zhu, Xiaochan;Fu, Nanyan;Guo, Yanyan;Chen, Yiping;Zhu, Xiaochan;Fu, Nanyan;Guo, Yanyan;Chen, Yiping;Zhu, Xiaochan;Fu, Nanyan;Pan, Zhizhen;Zhang, Xiangyu;Wang, Jian

作者机构：

关键词： Squaraine;Self-assembly;Nanosensor;Human serum albumin;Disaggregation;Fluorescent probe

期刊名称：SENSORS AND ACTUATORS B-CHEMICAL （ 影响因子：7.46； 五年影响因子：6.743 ）

ISSN： 0925-4005

年卷期： 2018 年 255 卷

页码：

收录情况： SCI

摘要： "Aggregation-caused signal change", a well-established mechanism, should not be ignored for sensing, while small molecule based on self-assembly and disaggregation has been studied and used for protein detection. In this work, we have synthesized a novel fluorescent chemosensor SQ with a polyether chain to enhance water solubility, and this has been used for the detection of human serum albumin (HSA) in aqueous solution with excellent sensitivity and selectivity. SQ was aggregated into nanoparticles with an average particle size of 458 nm in neutral solution and showed fluorescence silent due to the aggregation induced quenching. However, addition of HSA decreased the average particle size of SQ to 295 nm and released the fluorescence because of the reassembly of the SQ-HSA complex. More importantly, HSA could be selectively detected in the presence of other biological proteins and the main physiological inorganic anions and cations with the detection limit estimated as 15.6 nM according to 3 sigma/k. This versatile strategy suggests that squaraine dyes can be used as fluorescence-enhanced probes for the quantitative detection of HSA as well as in applications for the detection of HSA in urine samples. (C) 2017 Elsevier B.V. All rights reserved.

分类号：

  • 相关文献

[1]Loop-mediated isothermal amplification for visual detection of Vibrio parahaemolyticus using gold nanoparticles. Kong, Cong,Wang, Yuan,Yang, Guang-xin,Han, Feng,Fodjo, Essy Kouadio,Shen, Xiao-sheng. 2018

[2]Rapid tenderizing of goose breast muscle based on actomyosin dissociation by low-frequency ultrasonication. Zou, Ye,Bian, Huan,Zhang, Muhan,Sun, Chong,Xu, Weimin,Wang, Daoying,Zhang, Kun,Wang, Daoying. 2018

[3]High-pressure microfluidisation pretreatment disaggregate peanut protein isolates to prepare antihypertensive peptide fractions. Gong, Kuijie,Deng, Lei,Shi, Aimin,Liu, Hongzhi,Liu, Li,Hu, Hui,Wang, Qiang,Gong, Kuijie,Adhikari, Benu.

[4]An Improved Spatial Downscaling Procedure for TRMM 3B43 Precipitation Product Using Geographically Weighted Regression. Chen, Cheng,Zhao, Shuhe,Chen, Cheng,Zhao, Shuhe,Chen, Cheng,Zhao, Shuhe,Duan, Zheng,Qin, Zhihao. 2015

[5]Binding Characterization of Recombinant Odorant-binding Proteins from the Parasitic Wasp, Microplitis mediator (Hymenoptera: Braconidae). Zhang, Shuai.

[6]Imaging and Detection of Carboxylesterase in Living Cells and Zebrafish Pretreated with Pesticides by a New Near-Infrared Fluorescence Off-On Probe. Li, Dongyu,Li, Zhao,Yang, Xingbin,Chen, Weihua.

[7]Synthesis of Reversible Fluorescence Quenched Probe for Cu2+ and Imaging in PK-15 cells. Zhang Yingpeng,You Caixia,Yang Yunshang,Liu Xiaoyu,Dong Yuying,Guo Huichen. 2016

[8]Rational design and efficient synthesis of a fluorescent-labeled jasmonate. Liu, Songbai,Fu, Yuanqing,Sang, Ruocheng,Wang, Wu-Hong,Dang, Ya-Li.

[9]A novel solvent-dependently bifunctional NIR absorptive and fluorescent ratiometric probe for detecting Fe3+/Cu2+ and its application in bioimaging. Li, Shao,Ma, Saige,Liu, Yao,Xu, Zhanhui,Ye, Yong,Zhang, Di,Xie, Xinyu,Gao, Yanfeng.

[10]Based on SERS conformational studies of ginsenoside Rb1 and its metabolites before and after combined with human serum albumin. Zhang, Wei,Wang, Yingping,Bai, Xueyuan,Zhao, Bing.

[11]Investigation of the binding sites and orientation of caffeine on human serum albumin by surface-enhanced Raman scattering and molecular docking. Wang, Weinan,Duan, Yaokai,Jiang, Yong,Zhang, Liangren,Tu, Pengfei,Zhang, Wei,Zhao, Bing.

[12]SERS spectroscopy of kaempferol and galangin under the interaction of human serum albumin with adsorbed silver nanoparticles. Zhang, Wei,Bai, Xueyuan,Zhao, Daqing,Zhao, Yu,Zhang, Wei,Wang, Yingping,Zhao, Bing.

[13]Molecular Structure-Affinity Relationship of Flavonoids in Lotus Leaf (Nelumbo nucifera Gaertn.) on Binding to Human Serum Albumin and Bovine Serum Albumin by Spectroscopic Method. Tang, Xiaosheng,Tang, Xiaosheng,Tang, Xiaosheng,Tang, Ping,Liu, Liangliang,Tang, Ping.

[14]SERS study of different configurations of pharmaceutical and natural product molecules ginsenoside Rg3 under the interaction with human serum albumin on simple self-assembled substrate. Zhang, Wei,Wang, Yingping,Hou, Wei,Jin, Yinping,Bai, Xueyuan,Zhao, Yu,Zhao, Daqing,Zhao, Bing.

[15]Effects of gamma-Irradiation on the Molecular Structures and Functions of Human Serum Albumin. Hu, Xinxin,Song, Wei,Guo, Changying,Yu, Zehua,Liu, Rutao,Li, Wei,Guo, Changying.

[16]Sweet potato amylose and amylopectin with narrower distribution of molar mass and chain length obtained by a repeated retrogradation-hydrolysis procedure. Dong, Shirui,Zhao, Pei,Gao, Kai,Kang, Haiqi,Li, Lin,Li, Lin. 2016

[17]Coassembled nanostructured bioscaffold reduces the expression of proinflammatory cytokines to induce apoptosis in epithelial cancer cells. Li, Rui,Pavuluri, Sivapriya,Long, Benjamin M.,Pfeffer, Frederick M.,Nicholas, Kevin R.,Barrow, Colin J.,Williams, Richard J.,Bruggeman, Kiara,Nisbet, David R.,Parnell, Andrew J.,Martel, Anne,Dennison, Andrew J. C.,Parnell, Steven R.,Li, Rui,Pavuluri, Sivapriya,Nicholas, Kevin R.,Williams, Richard J.,Williams, Richard J.,Dennison, Andrew J. C.. 2016

[18]Structure and Properties of Self-assembled Narural Rubber/Multi-walled Carbon Nanotube Composites. Peng Zheng,Luo Yongyue,Feng Chunfang,Yi Zhifeng,Kong Lingxue. 2011

[19]A sequence-selective electrochemical DNA biosensor based on HRP-labeled probe for colorectal cancer DNA detection. Wang, Zhijie,Leng, Kailiang,Yang, Yunhui,Li, Jishan,Zheng, Fan,Shen, Guoli,Yu, Ruqin.

[20]Self-assembled natural rubber/silica nanocomposites: Its preparation and characterization. Peng, Zheng,Kong, Ling Xue,Li, Si-Dong,Chen, Yin,Huang, Mao Fang. 2007

作者其他论文 更多>>

微信小程序