Metabolomics reveals changes in metabolite concentrations and correlations during sexual development of Eurotium cristatum (synonym: Aspergillus cristatus)

文献类型： 外文期刊

第一作者： Ren, C. G.

作者： Ren, C. G.;Ren, C. G.;Ren, C. G.;Tan, Y. M.;Liu, Y. X.;Tan, Y. M.;Liu, Y. X.;Liu, Z. Y.;Ren, X. X.

作者机构：

关键词： Eurotium cristatum;Fungus;Metabolite;metabolite correlation;Metabolomic

期刊名称：MYCOSPHERE （ 影响因子：4.211； 五年影响因子：2.866 ）

ISSN： 2077-7000

年卷期： 2017 年 8 卷 10 期

页码：

收录情况： SCI

摘要： Eurotium cristatum is the main probiotic fungus involved in fermentation of Chinese Fuzhuan brick tea, and the amount of E. cristatum is an important indicator of tea quality. Sexual development of E. cristatum consists of three main stages, hypha and ascogonium (at 36 hours post-inoculation), cleistothecium formation (at 48 hours), and cleistothecium ripening (at 72 hours), and each stage exhibits a unique metabolite profile. In this study, developmental changes were analyzed by GC-MS based untargeted metabolomics. Ninety-nine metabolites involved in multiple biochemical pathways were identified. Principal component analysis separated developing E. cristatum into 36, 48 and 72 hour groups. Hierarchical cluster analyses showed that the relative contents of organic acids and amino acids peaked at 36 hours and decreased thereafter, while alcohol and carbohydrate levels peaked at 48-72 hours. Statistical analysis revealed 401 significant metabolite-metabolite correlations (Pearson's vertical bar r vertical bar>0.8 at a false discovery rate <= 0.05), of which 213 were positive and 188 negative. The early increases in organic acid and amino acid metabolites as well as certain phosphate and amine metabolites favor ascogonium formation. Conversely, increased alcohol and carbohydrate concentrations favor cleistothecium formation. These results provide a foundation for further exploration of the biochemical mechanism underlying sexual development in E. cristatum.

分类号：

  • 相关文献

[1]Physiological characteristics and metabolomics of transgenic wheat containing the maize C-4 phosphoenolpyruvate carboxylase (PEPC) gene under high temperature stress. Qi, Xueli,Qi, Xueli,Xu, Weigang,Zhang, Jianzhou,Guo, Rui,Zhao, Mingzhong,Hu, Lin,Wang, Huiwei,Dong, Haibin,Li, Yan.

[2]Comparative Proteomic Analysis of Gossypium thurberi in Response to Verticillium dahliae Inoculation. Weiping Fang,Deyi Xie,Heqin Zhu,Wu Li,Zhenzhen Xu,Lirong Yang,Zhifang Li,Li Sun,Jinxia Wang,Lihong Nie,Zhongjie Tang,Shuping Lv,Fu’an Zhao,Yao Sun,Yuanming Zhao,Jianan Hou,Xiaojie Yang. 2015

[3]Phytopathogenic fungus hosts a plant virus: A naturally occurring cross-kingdom viral infection. Andika, Ida Bagus,Wei, Shuang,Salaipeth, Lakha,Sun, Liying,Andika, Ida Bagus,Wei, Shuang,Salaipeth, Lakha,Sun, Liying,Andika, Ida Bagus,Kondo, Hideki,Cao, Chunmei,Salaipeth, Lakha.

[4]Spiculisporic acid analogues of the marine-derived fungus, Aspergillus candidus strain HDf2, and their antibacterial activity. Wang, Rong,Li, Xiang Min,Chen, Fu Xiao,Zhan, Xia Fei,Shen, Ming Hui,Guo, Zhi Kai.

[5]Mycangial fungus benefits the development of a leaf-rolling weevil, Euops chinesis. Ding, Jianqing,Li, Xiaoqiong,Guo, Wenfeng.

[6]Antimicrobial activity of an endophytic Xylaria sp.YX-28 and identification of its antimicrobial compound 7-amino-4-methylcoumarin. Liu, Xiaoli,Dong, Mingsheng,Chen, Xiaohong,Jiang, Mei,Lv, Xin,Lv, Xin,Zhou, Jianzhong.

[7]Transformation of the endophytic fungus Acremonium implicatum with GFP and evaluation of its biocontrol effect against Meloidogyne incognita. Yao, Yu-Rong,Tian, Xue-Liang,Shen, Bao-Ming,Mao, Zhen-Chuan,Chen, Guo-hua,Xie, Bing-Yan,Tian, Xue-Liang,Shen, Bao-Ming.

[8]Molecular mechanism of BjCHI1-mediated plant defense against Botrytis cinerea infection. Gao, Ying,Zhao, Kaijun. 2017

[9]Carbon: Nitrogen: Phosphorus Stoichiometry in Fungi: A Meta-Analysis. Zhang, Ji,Zhang, Ji,Elser, James J.,Elser, James J.. 2017

[10]Transcriptome analysis reveals the complexity of alternative splicing regulation in the fungus Verticillium dahliae. Jin, Lirong,Yu, Dazhao,Huang, Wei,Li, Guanglin,Cheng, Chao,Liao, Shengjie,Zhang, Yi,Liao, Shengjie,Wu, Qijia,Zhang, Yi,Li, Guanglin,Wu, Qijia. 2017

[11]Chrodrimanins O-S from the fungus Penicillium. sp SCS-KFD09 isolated from a marine worm, Sipunculusnudus. Kong, Fan-Dong,Ma, Qing-Yun,Xie, Qing-Yi,Wang, Pei,Chen, Peng-Wei,Zhou, Li-Man,Dai, Hao-Fu,Zhao, You-Xing,Luo, Du-Qiang,Zhang, Ren-Shuai. 2017

[12]BjMYB1, a transcription factor implicated in plant defence through activating BjCHI1 chitinase expression by binding to a W-box-like element. Gao, Ying,Jia, Shuangwei,Wang, Chunlian,Wang, Fujun,Wang, Fajun,Zhao, Kaijun.

[13]Impact of Herbicide 2, 4-Dichlorophenoxyacetic Acid Butyl Ester on Soil Nitrogen-transforming Bacterial Populations in Two Soils. Ding, Hong,Zhang, Jing,Fang, Yu,Zheng, Xiangzhou,Zhang, Yushu,Chen, Deli. 2017

[14]New Nematotoxic Indoloditerpenoid Produced by Gymnoascus reessii za-130. Liu, Ting,Dong, Dan,Zhang, TaoTao,Liu, Wei-cheng,Meyer, Susan L. F.,Chitwood, David J.,Chauhan, Kamlesh R.,Li, Jun.

[15]Dissipation of pyraclostrobin and its metabolite BF-500-3 in maize under field conditions. You, Xiangwei,Liu, Congyun,Liu, Fengmao,Liu, Yanping,Dong, Jiannan,Liu, Congyun,Liu, Yanping.

[16]Identification of pinostilbene as a major colonic metabolite of pterostilbene and its inhibitory effects on colon cancer cells. Sun, Yue,Qiu, Peiju,Zhang, Lijuan,Sun, Yue,Wu, Xian,Cai, Xiaokun,Song, Mingyue,Zheng, Jinkai,Pan, Che,Qiu, Peiju,Xiao, Hang,Zhou, Shuangde,Tang, Zhonghai,Xiao, Hang,Zheng, Jinkai.

[17]Flavonoid Metabolites in Human Urine during Blueberry Anthocyanin Intake. Kalt, Wilhelmina,McDonald, Jane E.,Fillmore, Sherry A. E.,Liu, Yan.

[18]Enantioselective metabolism and toxic effects of metalaxyl on primary hepatocytes from rat. Wang, Xinru,Zhu, Wentao,Zhang, Ping,Wang, Yao,Zhou, Zhiqiang,Qiu, Jing.

[19]Simultaneous determination of penflufen and one metabolite in vegetables and cereals using a modified quick, easy, cheap, effective, rugged, and safe method and liquid chromatography coupled to tandem mass spectrometry. Tian, Fajun,Liu, Xingang,Xu, Jun,Dong, Fengshou,Wu, Xiaohu,Zheng, Yongquan,Tian, Fajun,Wu, Yanbing.

[20]Determination of cyantraniliprole and its major metabolite residues in vegetable and soil using ultra-performance liquid chromatography/tandem mass spectrometry. Liu, Xingang,Xu, Jun,Li, Jing,Li, Yuanbo,Zheng, Yongquan,Shan, Weili,Song, Wencheng.

作者其他论文 更多>>

微信小程序