Marine peptides as potential anti-aging agents: Preparation, characterization, mechanisms of action, and future perspectives

文献类型： 外文期刊

第一作者： Yao, Wanzi

作者： Yao, Wanzi;Zhang, Yifeng;Zhang, Gaiping;Zhang, Gaiping;Zhang, Gaiping;Zhang, Gaiping;Zhang, Gaiping

作者机构：

关键词： Marine peptides; Anti-aging; Preparation; Mechanisms; Oxidative stress; Signaling pathways

期刊名称：FOOD CHEMISTRY （ 影响因子：8.5； 五年影响因子：8.2 ）

ISSN： 0308-8146

年卷期： 2024 年 460 卷

页码：

收录情况： SCI

摘要： Aging is a universal biological process characterized by a decline in physiological functions, leading to increased susceptibility to diseases. With global aging trends, understanding and mitigating the aging process is paramount. Recent studies highlight marine peptides as promising bioactive substances with potential anti-aging properties. This review critically examines the potential of marine peptides as novel food ingredients in antiaging, exploring their sources, preparation methods, physicochemical properties, and the underlying mechanisms through which they impact the aging process. Marine peptides exhibit significant potential in targeting aging, extending lifespan, and enhancing healthspan. They act through mechanisms such as reducing oxidative stress and inflammation, modulating mitochondrial dysfunction, inducing autophagy, maintaining extracellular matrix homeostasis, and regulating longevity-related pathways. Despite challenges in stability, bioavailability, and scalability, marine peptides offer significant potential in health, nutraceuticals, and pharmaceuticals, warranting further research and development in anti-aging.

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