Recent advances in the exploration and discovery of SARS-CoV-2 inhibitory peptides from edible animal proteins
文献类型: 外文期刊
作者: Kong, Xiaoyue 1 ; Wang, Wei 2 ; Zhong, Yizhi 3 ; Wang, Nan 4 ; Bai, Kaiwen 2 ; Wu, Yi 2 ; Qi, Qianhui 2 ; Zhang, Yu 5 ; Liu, Xingquan 1 ; Xie, Junran 3 ;
作者机构: 1.Zhejiang Agr & Forestry Univ, Coll Food & Hlth, Hangzhou, Peoples R China
2.Zhejiang Univ Sci & Technol, Sch Biol & Chem Engn, Hangzhou, Peoples R China
3.Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Anesthesiol, Hangzhou, Peoples R China
4.Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou, Peoples R China
5.Zhejiang Acad Agr Sci, Inst Qual & Stand Agr Prod, Hangzhou, Peoples R China
关键词: efficacy; mechanisms; peptides derived from animal proteins; SARS-CoV-2; computer-aided design methods; drug delivery strategies
期刊名称:FRONTIERS IN NUTRITION ( 影响因子:5.0; 五年影响因子:5.7 )
ISSN: 2296-861X
年卷期: 2024 年 11 卷
页码:
收录情况: SCI
摘要: The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), is spreading worldwide. Although the COVID-19 epidemic has passed its peak of transmission, the harm it has caused deserves our attention. Scientists are striving to develop medications that can effectively treat COVID-19 symptoms without causing any adverse reactions. SARS-CoV-2 inhibitory peptides derived from animal proteins have a wide range of functional activities in addition to safety. Identifying animal protein sources is crucial to obtaining SARS-CoV-2 inhibitory peptides from animal sources. This review aims to reveal the mechanisms of action of these peptides on SARS-CoV-2 and the possibility of animal proteins as a material source of SARS-CoV-2 inhibitory peptides. Also, it introduces the utilization of computer-aided design methods, phage display, and drug delivery strategies in the research on SARS-CoV-2 inhibitor peptides from animal proteins. In order to identify new antiviral peptides and boost their efficiency, we recommend investigating the interaction between SARS-CoV-2 inhibitory peptides from animal protein sources and non-structural proteins (Nsps) using a variety of technologies, including computer-aided drug approaches, phage display techniques, and drug delivery techniques. This article provides useful information for the development of novel anti-COVID-19 drugs.
- 相关文献
作者其他论文 更多>>
-
Stimuli-responsive biodegradable silica nanoparticles: From native structure designs to biological applications
作者:Qi, Qianhui;Wang, Wei;Shen, Qian;Geng, Jiaying;An, Weizhen;Wu, Qiong;Yu, Changmin;Shen, Qian;Geng, Jiaying;An, Weizhen;Wu, Qiong;Yu, Changmin;Qi, Qianhui;Yu, Changmin;Wang, Nan;Zhang, Yu;Li, Xue;Li, Lin
关键词:Biodegradation; Silica nanoparticles; Stimuli -responsive; Multiple frameworks; Biological applications
-
Metabonomics and Transcriptomics Analyses Reveal the Development Process of the Auditory System in the Embryonic Development Period of the Small Yellow Croaker under Background Noise
作者:Jiang, Qinghua;Liang, Xiao;Ye, Ting;Zhang, Yu;Lou, Bao
关键词:Larimichthys polyactis; auditory system; embryonic development; background noise; metabonome; transcriptome
-
Comparative analysis of asparagus tea processing and flavor component analysis
作者:Zhang, Huaizhen;Wang, Jie;Wang, Hao;Cheng, Chenxia;Zhang, Xinfu;Xue, Junxiu;Li, Tengteng;Yang, Shaolan;Zhang, Yu;Zhou, Suping;Li, Baohua
关键词:Asparagus tea; Blanching; Volatile compounds; Gas chromatography-mass spectrometry; Orthogonal partial least squares-discriminant; analysis
-
Visible/near-infrared Spectroscopy and Hyperspectral Imaging Facilitate the Rapid Determination of Soluble Solids Content in Fruits
作者:Zhao, Yiying;Zhang, Xiaobin;Gu, Qing;Zhu, Yihang;Zhou, Lei;Wang, Wei;Chen, Rongqin;Zhang, Chu
关键词:VIS/NIR spectroscopy; Hyperspectral imaging; Fruit SSC; Data acquisition and analysis; Internal and external interference; Compensation strategy
-
Faecal hsa-miR-7704 inhibits the growth and adhesion of Bifidobacterium longum by suppressing ProB and aggravates hepatic encephalopathy
作者:Wang, Yuchong;Li, Yuyu;Lv, Longxian;Hong, Liang;Zhang, Yu;Diao, Hongyan;Zhu, Liying;Wang, Xin;Wang, Xueyao
关键词:
-
Multi-phenotype response and cadmium detection of rice stem under toxic cadmium exposure
作者:Wang, Wei;Wang, Leiping;Xiao, Hang;Wang, Wei;Man, Zun;Li, Xiaolong;Chen, Rongqin;Pan, Tiantian;Liu, Fei;Wang, Wei;Wang, Leiping;Xiao, Hang;Zhao, Yiying;Dai, Xiaorong
关键词:Rice stem; Cadmium; Plant phenotype; Lipid peroxidation; Laser-induced breakdown spectroscopy; Machine learning
-
Effect of ultrasonic treatment during fermentation on the quality of fortified sweet wine
作者:Liu, Xinyang;Bai, Yangyang;Chen, Qiaomin;Han, Fuliang;Liu, Xinyang;Wang, Xinquan;Hu, Guixian;Wang, Junhong;Bai, Liping;Zhang, Yu;Duan, Changqing;Han, Fuliang;Du, Juan;Han, Fuliang;Zhang, Yu;Zhang, Yu
关键词:Fortified wines; Aged wines; Ultrasonic bath; Anthocyanin; Ethyl carbamate; Volatile compound; Sensory analysis