您好，欢迎访问浙江省农业科学院 机构知识库！
浙江省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Recent advances in the exploration and discovery of SARS-CoV-2 inhibitory peptides from edible animal proteins

文献类型： 外文期刊

作者： Kong, Xiaoyue 1 ; Wang, Wei 2 ; Zhong, Yizhi 3 ; Wang, Nan 4 ; Bai, Kaiwen 2 ; Wu, Yi 2 ; Qi, Qianhui 2 ; Zhang, Yu 5 ; Liu, Xingquan 1 ; Xie, Junran 3 ;

作者机构： 1.Zhejiang Agr & Forestry Univ, Coll Food & Hlth, Hangzhou, Peoples R China

2.Zhejiang Univ Sci & Technol, Sch Biol & Chem Engn, Hangzhou, Peoples R China

3.Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Anesthesiol, Hangzhou, Peoples R China

4.Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou, Peoples R China

5.Zhejiang Acad Agr Sci, Inst Qual & Stand Agr Prod, Hangzhou, Peoples R China

关键词： efficacy; mechanisms; peptides derived from animal proteins; SARS-CoV-2; computer-aided design methods; drug delivery strategies

期刊名称：FRONTIERS IN NUTRITION （ 影响因子：5.0； 五年影响因子：5.7 ）

ISSN： 2296-861X

年卷期： 2024 年 11 卷

页码：

收录情况： SCI

摘要： The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), is spreading worldwide. Although the COVID-19 epidemic has passed its peak of transmission, the harm it has caused deserves our attention. Scientists are striving to develop medications that can effectively treat COVID-19 symptoms without causing any adverse reactions. SARS-CoV-2 inhibitory peptides derived from animal proteins have a wide range of functional activities in addition to safety. Identifying animal protein sources is crucial to obtaining SARS-CoV-2 inhibitory peptides from animal sources. This review aims to reveal the mechanisms of action of these peptides on SARS-CoV-2 and the possibility of animal proteins as a material source of SARS-CoV-2 inhibitory peptides. Also, it introduces the utilization of computer-aided design methods, phage display, and drug delivery strategies in the research on SARS-CoV-2 inhibitor peptides from animal proteins. In order to identify new antiviral peptides and boost their efficiency, we recommend investigating the interaction between SARS-CoV-2 inhibitory peptides from animal protein sources and non-structural proteins (Nsps) using a variety of technologies, including computer-aided drug approaches, phage display techniques, and drug delivery techniques. This article provides useful information for the development of novel anti-COVID-19 drugs.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：浙江省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台