文献类型： 外文期刊

作者： Sheng, Xin-Yuan ¹ ; Zhang, Hai-Jiang ² ; Chen, Xin-Juan ³ ; Wang, Kui-Wu ¹ ;

作者机构： 1.Zhejiang Gongshang Univ, Sch Food Sci & Biotechnol, Hangzhou 310018, Peoples R China

2.Huaiyin Inst Technol, Jiangsu Key Lab Reg Specif Resource Pharmaceut Tra, Huaian 223003, Peoples R China

3.Zhejiang Acad Agr Sci, Inst Vegetable, Hangzhou 310021, Peoples R China

关键词： Benincasa hispida var. Chieh-qua How; Polysaccharide degradation; Response surface methodology (RSM); Antioxidant activity; Anti-tyrosinase activity

期刊名称：CHEMISTRY & BIODIVERSITY （ 影响因子：2.5； 五年影响因子：2.6 ）

ISSN： 1612-1872

年卷期： 2025 年 22 卷 3 期

页码：

收录情况： SCI

摘要： This study reported an effective method for the degradation of Chieh-qua (Benincasa hispida var. Chieh-qua How) polysaccharides (BHCP) by a hydrogen peroxide-ascorbic acid oxidation (H2O2-VC) system. The degradation conditions were optimized using a Box-Behnken response surface design as concentration of H2O2-VC 19.5 mM, degradation temperature 46.4 degrees C and degradation time 1.0 h. The average molecular weight was decreased and total sugar content was raised of the degraded polysaccharide (DBHCP). Two refined degraded polysaccharides (DBHCP-1, DBHCP-2) were purified and prepared, and their structures were analyzed by chemical and spectral analysis. The in vitro experiments showed that degraded polysaccharides (DBHCP and DBHCP-1) have better antioxidant and anti-tyrosinase activity than natural polysaccharide BHCP. These findings support the potential application of Chieh-qua polysaccharides in the food and medical industries.