文献类型： 外文期刊

作者： Xia, Zhiqiang ¹ ; Du, Zhenglin ² ; Zhou, Xincheng ¹ ; Jiang, Sirong ¹ ; Zhu, Tingting ⁵ ; Wang, Le ⁵ ; Chen, Fei ¹ ; Carvalho, Luiz ⁷ ; Zou, Meiling ¹ ; Lopez-Lavalle, Luis Augusto Becerra ⁸ ; Zhang, Xiaofei ⁸ ; Xu, Liangye ¹ ; Wang, Zhenyu ⁹ ; Chen, Meili ² ; Guo, Xin ¹ ; Wang, Shujuan ¹ ; Li, Mengtao ¹ ; Li, Yuanchao ¹⁰ ; Wang, Haiyan ⁴ ; Liu, Shisheng ¹ ; Bao, Yuting ¹ ; Zhao, Long ¹¹ ; Zhang, Chenji ¹ ; Xiao, Jianjia ¹ ; Guo, Fengguang ¹ ; Shen, Xu ¹ ; Li, Haozheng ¹ ; Lu, Cheng ⁴ ; Qiao, Fei ⁶ ; Ceballos, Hernan ⁸ ; Yan, Huabing ¹² ; Qin, Xiaochun ¹³ ; Ma, Ling ¹³ ; Zhang, Huaifang ¹ ; He, Shuang ¹ ; Zhao, Wenming ² ; Wan, Yinglang ¹ ; Chen, Yinhua ¹ ; Huang, Dongyi ¹ ; Li, Kaimian ⁶ ; Li, Bin ¹ ; Peng, Ming ¹ ; Zhang, Weixiong ¹⁴ ; Moller, Birger Lindberg ¹⁵ ; Chen, Xin ¹ ; Luo, Ming-Cheng ⁵ ; Xiao, Jingfa ² ; Wang, Wenquan ¹ ;

作者机构： 1.Hainan Univ, Natl Key Lab Biotechnol & Breeding Trop Crops, Haikou 570228, Peoples R China

2.Chinese Acad Sci, Beijing Inst Genom, Natl Genom Data Ctr, Beijing 100101, Peoples R China

3.China Natl Ctr Bioinformat, Beijing 100101, Peoples R China

4.Chinese Acad Trop Agr Sci CATAS, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

5.Univ Calif Davis, Dept Plant Sci, Davis, CA 95616 USA

6.Chinese Acad Trop Agr Sci CATAS, Inst Trop Crop Genet Resources, Haikou 571700, Peoples R China

7.Brazilian Enterprise Agr Res EMBRAPA, Genet Resources & Biotechnol, BR-70770 Brasilia, Brazil

8.Int Ctr Trop Agr CIAT, Cali 6713, Colombia

9.Guangdong Acad Sci, Inst Nanfan & Seed Ind, Guangzhou 510316, Peoples R China

10.Guangxi Univ, Coll Life Sci & Technol, State Key Lab Conservat & Utilizat Subtrop Agrobio, Nanning 530004, Peoples R China

11.Qinghai Univ, Acad Agr & Forestry Sci, Xining 810016, Peoples R China

12.Guangxi Acad Agr Sci, Econ Crops Inst, Nanning, Peoples R China

13.Univ Jinan, Sch Biol Sci & Technol, Jinan, Peoples R China

14.Hong Kong Polytech Univ, Dept Hlth Technol & Informat, Dept Comp, Hong Kong, Peoples R China

15.Univ Copenhagen, Dept Plant & Environm Sci, Plant Biochem Lab, DK-1871 Frederiksberg C, Denmark

关键词： genome; pan-genome; structural variations; selective sweeping; evolution and domestication; cassava

期刊名称：MOLECULAR PLANT （ 影响因子：24.1； 五年影响因子：25.8 ）

ISSN： 1674-2052

年卷期： 2025 年 18 卷 6 期

页码：

收录情况： SCI

摘要： Cassava is a highly resilient tropical crop that produces large, starchy storage roots and high biomass. However, how did cassava's remarkable environmental adaptability and key economic traits evolve from its wild species remain unclear. In this study, we obtained near complete telomere-to-telomere genome assemblies and their haplotype forms for the cultivar AM560, the wild ancestors FLA4047 and W14, constructed a graphic pan-genome of 30 representatives with a size of 1.15 Gb, and built a clarified evolutionary tree of 486 accessions. A comparison of structural variations and single-nucleotide variations between the ancestors and cultivated cassavas reveals predominant expansions and contractions of numbers of genes and gene families, which are mainly driven by transposons. Significant selective sweeping occurred in 122 footprints of genomes and affects 1,519 domesticated genes. We identify selective mutations in MeCSK and MeFNR2 that could promote photoreactions associated with MeNADP-ME in C4 photosynthesis in modern cassava. Coevolution of retard floral primordia and initiation of storage roots may arise from Me-COL5 variants with altered bindings to MeFT1, MeFT2, and MeTFL2. Mutations in MeMATE1 and MeGTR occur in sweet cassava, and MeAHL19 has evolved to regulate the biosynthesis, transport, and endogenous remobilization of cyanogenic glucosides in cassava. These extensive genomic and gene resources provided here, along with the findings on the evolutionary mechanisms responsible for beneficial traits in modern cultivars, lay a strong foundation for future breeding improvements of cassava.