Molecular characterization, expression pattern and immunologic function of CD82a in large yellow croaker (Larimichthys crocea)
文献类型： 外文期刊
作者： Liu, Yue 1 ; Bai, Yulin 1 ; Chen, Sijing 1 ; Pu, Fei 1 ; Li, Yaxian 1 ; Chi, Hongshu 2 ; Zheng, Zaiyu 2 ; Xu, Peng 1 ; Zhou, Tao 1 ;
作者机构： 1.Xiamen Univ, Coll Ocean & Earth Sci, State Key Lab Mariculture Breeding, Xiamen, Peoples R China
2.Fujian Acad Agr Sci, Biotechnol Inst, Fuzhou, Fujian, Peoples R China
3.Xiamen Univ, Coll Ocean & Earth Sci, Fujian Key Lab Genet & Breeding Marine Organisms, Xiamen, Peoples R China
关键词： Larimichthys crocea; Pseudomonas plecoglossicida; CD82a; apoptosis; antigen presentation
期刊名称：FRONTIERS IN IMMUNOLOGY （ 影响因子：7.3； 五年影响因子：8.0 ）
ISSN： 1664-3224
年卷期： 2024 年 15 卷
页码：
收录情况： SCI
摘要： Visceral white spot disease (VWND) caused by Pseudomonas plecoglossicida poses a major threat to the sustainable development of large yellow croaker (Larimichthys crocea) aquaculture. Genome-wide association analysis (GWAS) and RNA-seq research indicated that LcCD82a play an important role in resistance to visceral white spot disease in L. crocea, but the molecular mechanism of LcCD82a response to P. plecoglossicida infection is still unclear. In this study, we cloned and validated the Open Reading Frame (ORF) sequence of LcCD82a and explored the expression profile of LcCD82a in various tissues of L.crocea. In addition, two different transcript variants (LcCD82a-L and LcCD82a-S) of LcCD82a were identified that exhibit alternative splicing patterns after P. plecoglossicida infection, which may be closely related to the immune regulation during pathogenetic process of VWND. In order to explore the function of LcCD82a, we purified the recombinant protein of LcCD82a-L and LcCD82a-S. The bacterial agglutination and apoptosis function analysis showed that LcCD82a may involve in extracellular bacterial recognition, agglutination, and at the same time participate in the process of antigen presentation and induction of cell apoptosis. Collectively, our studies demonstrate that LcCD82a plays a crucial role in regulating apoptosis and antimicrobial immunity.
- 相关文献
作者其他论文 更多>>
-
Application of selection Index for enhancing resistance to Cryptocarya irritans and Vibrio alginolyticus in large yellow croaker
作者：Wang, Jiaying;Zhao, Ji;Jiang, Pengxing;Xiao, Junzu;Jiang, Zhou;Miao, Lingwei;He, Qian;Zeng, Junjia;Ke, Qiaozhen;Zhou, Tao;Xu, Peng;Wang, Jiaying;Zhao, Ji;Jiang, Pengxing;Xiao, Junzu;Jiang, Zhou;Miao, Lingwei;He, Qian;Zeng, Junjia;Ke, Qiaozhen;Zhou, Tao;Xu, Peng;Liu, Bo;Chi, Hongshu
关键词：selection index; disease resistance trait; genomic selection; large yellow croaker; aquaculture
-
Fungal diversity notes 1919-2016: taxonomic and phylogenetic contributions to fungal taxa
作者：Cao, Bin;Wang, Long;Li, Jia-Xin;Han, Xi-Xi;Yang, Wen-Qiang;Wang, Shi-Hui;He, Mao-Qiang;Zhao, Rui-Lin;Cao, Bin;Phurbu, Dorji;Zhao, Rui-Lin;Ralaiveloarisoa, Anna;Liimatainen, Kare;Niskanen, Tuula;Liimatainen, Kare;Niskanen, Tuula;Ramirez-Cruz, Virginia;Cortes-Perez, Alonso;Guzman-Davalos, Laura;Castro-Jauregui, Oscar;Bradshaw, Alexander James;Dentinger, Bryn T. M.;Dentinger, Bryn T. M.;Ramirez-Guillen, Florencia;Villalobos-Arambula, Alma Rosa;da Silva, Paula Santos;Day, Rory;Davoodian, Naveed;Lebel, Teresa;May, Tom W.;Lebel, Teresa;Castellano, Michael;Toome, Merje;Vasey, Jack;Hofer, Katharina;Thangavel, Rajaram;Braithwaite, Mark;Braithwaite, Lewis;Dutta, Arun Kumar;Chattopadhyay, Pinaki;Roy, Niranjan;Tanti, Bhaben;Biswas, Pinky Rani;Roy, Niranjan;Arumugam, Elangovan;Kezo, Kezhocuyi;Kaliyaperumal, Malarvizhi;Murugadoss, Ramesh;Ji, Jing-Xin;Kakishima, Makoto;Cooper, Jerry;Nuytinck, Jorinde;Lagaet, Phaedra;De Lange, Ruben;Verbeken, Annemieke;Tondeleir, Lowie;Nuytinck, Jorinde;Luo, Zong-Long;Wang, Wen-Peng;Zhang, Xian;Li, Hua;Xiong, Yin-Ru;Wu, Na;Shu, Yong-Xin;Zhao, Hai-Jun;Liao, Chun-Fang;Yang, Hong-De;Jayawardena, Ruvishika Shehali;Thongklang, Naritsada;Han, Xi-Xi;Hyde, Kevin D.;Zhang, Xian;Wen, Ting-Chi;Zhang, Xian;Wen, Ting-Chi;Jia, Ao-Li;Fan, Xin-Lei;Jiang, Ning;Jiao, Ning;Zhang, Ying;Manawasinghe, Ishara S.;Li, Hua;Xiong, Yin-Ru;Zhou, Tao;Tan, Qing-Ling;Li, Hua;Xiong, Yin-Ru;Wu, Na;Shu, Yong-Xin;Zhao, Hai-Jun;Liao, Chun-Fang;Yang, Hong-De;Jayawardena, Ruvishika Shehali;Thongklang, Naritsada;Han, Xi-Xi;Hoshino, Tamotsu;Hoshino, Tamotsu;Manz, Cathrin;Hampe, Felix;Zhao, Chang-Lin;Yang, Yang;Zhang, Gui-Qing;Dai, Dong-Qin;Tomsovsky, Michal;Denchev, Teodor T.;Denchev, Cvetomir M.;Denchev, Teodor T.;Denchev, Cvetomir M.;Kemler, Martin;Leveille-Bourret, Etienne;Kemler, Martin;Chen, Yan-Peng;Maharachchikumbura, Sajeewa S. N.;Liu, Jian-Kui;Du, Hong-Zhi;Wu, Na;Feng, Zi-Xuan;Wang, Qi-Ming;Wan, Shan-Ping;Yu, Fu-Qiang;Yu, Fu-Qiang;Du, Hong-Zhi;Du, Hong-Zhi;Hu, Hong-Li;Su, Ji-Yu;Wang, Zong-Hua;Hu, Yan-Ping;Yu, Hao;Wang, Zong-Hua;Wang, Jing;Yang, Yi-Hua;Dong, Wei;Shu, Yong-Xin;Zhao, Hai-Jun;Liao, Chun-Fang;Doilom, Mingkwan;Wang, Chao-Qun;Xia, Wen-Xiao;Li, Guo-Jie;Suwannarach, Nakarin;Senwanna, Chanokned;Suwannarach, Nakarin;Senwanna, Chanokned;Gafforov, Yusufjon;Gafforov, Yusufjon;Flakus, Adam;Suchan, Tomasz;Rodriguez-Flakus, Pamela;Plata, Oscar;Tamang, Juna;Acharya, Krishnendu;Tiendrebeogo, Assiata;Somda, Irenee;Decock, Cony;Tiendrebeogo, Assiata;Legreve, Anne;Yang, Yu;Xiao, Yuan-Pin;Zhou, Xian-Zhi;Li, Jia-Xin;Zhao, Rui-Lin;Wang, Shi-Hui;He, Mao-Qiang
关键词：Ascomycota; Basidiomycota; New combination; New genus; New name; New record; New species
-
Detecting Deleterious Recessive Variants in Large Yellow Croaker Using Data from 7337 Individuals
作者：Jiang, Zhou;Zhao, Ji;Li, Ning;Wang, Jiaying;Pu, Fei;Xu, Peng;Zhou, Tao;Jiang, Zhou;Zhao, Ji;Li, Ning;Wang, Jiaying;Pu, Fei;Xu, Peng;Zhou, Tao;Zhao, Ji;Chi, Hongshu
关键词：Recessive alleles; Lethal mutations; Large yellow croaker; Homozygosity
-
A comprehensive analysis of the genomic and proteomic profiles of a megalocytivirus isolated from Larimichthys crocea
作者：Liu, Xiaodong;Chi, Hongshu;Yang, Xixi;Zheng, Zaiyu;Wu, Yunkun;Gong, Hui;Liu, Xiaodong;Chi, Hongshu;Yang, Xixi;Zheng, Zaiyu;Wu, Yunkun;Gong, Hui;Zhu, Chunhua;Chang, Wei-Jen;Gong, Hui
关键词：genome; megalocytivirus;
Larimichthys crocea ; GO analysis; proteome; electron microscopy; phylogenetic analysis -
Novel Eel Skin Fibroblast Cell Line: Bridging Adherent and Suspension Growth for Aquatic Applications Including Virus Susceptibility
作者：Zheng, Zaiyu;Chen, Bin;Liu, Xiaodong;Chi, Hongshu;Chen, Xiuxia;Pan, Ying;Gong, Hui;Guo, Rui
关键词：
Anguilla anguilla ; suspension growth; reversible adherent-suspension culture system; Anguillid herpesvirus; red-spotted grouper nervous necrosis virus -
Biochar affects organic carbon composition and stability in highly acidic tea plantation soil
作者：Li, Qiang;Zhang, Junchuan;Liu, Yue;Yi, Zhigang;Li, Qiang;Ye, Jing;Lin, Yi;Wang, Yixiang
关键词：Biochar; Soil organic carbon; Highly acidic soil; Soil organic carbon stability; Tea garden
-
Population structure and genome-wide evolutionary signatures reveal putative climate-driven habitat change and local adaptation in the large yellow croaker
作者：Chen, Baohua;Bai, Yulin;Wang, Jiaying;Ke, Qiaozhen;Zhou, Zhixiong;Zhou, Tao;Pan, Ying;Xu, Peng;Chen, Baohua;Ke, Qiaozhen;Zheng, Weiqiang;Xu, Peng;Chen, Baohua;Xu, Peng;Pan, Ying;Wu, Renxie;Wu, Xiongfei
关键词：Climate adaptation; Habitat change; Large yellow croaker; Phylogeographic structure
