Guadipyr, a new insecticide, induces microbiota dysbiosis and immune disorders in the midgut of silkworms (Bombyx mori)
文献类型： 外文期刊
作者： Hou, Jiayin 1 ; Yu, Jianzhong 1 ; Qin, Zhaohai 2 ; Liu, Xinju 1 ; Zhao, Xueping 1 ; Hu, Xiuqing 1 ; Yu, Ruixian 1 ; Wang, 1 ;
作者机构： 1.Zhejiang Acad Agr Sci, Inst Agroprod Safety & Nutr, State Key Lab Managing Biot & Chem Threats Qual, Hangzhou 310021, Zhejiang, Peoples R China
2.China Agr Univ, Coll Sci, Dept Appl Chem, Beijing 100083, Peoples R China
关键词： Guadipyr; Midgut microbiota; Immune disorder; Silkworm
期刊名称：ENVIRONMENTAL POLLUTION （ 影响因子：8.071； 五年影响因子：8.35 ）
ISSN： 0269-7491
年卷期： 2021 年 286 卷
页码：
收录情况： SCI
摘要： Guadipyr, which combines neonicotinoid and semicarbazone functional groups in one molecule, exhibits good activity on several pests and high acute and chronic toxicity to silkworms (Bombyx mori). In this report, the effects of low-dose guadipyr on the midgut microbiota and immune system of silkworms were studied. Results showed that the structure and richness of the midgut microbiota of silkworms were altered after being treated with 5.25 mg/L (1/10 of LC50) of guadipyr. The abundance of Pseudomonas was evidently increased, whereas Curvibacter was substantially reduced, which might be related to the growth and immunity of silkworms. The expression of key genes in the Toll, IMD, and JAK/STAT pathways, which ultimately led to the downregulation of antimicrobial peptide genes (AMPs), such as CecA, Defensin1, Leb, and glv2, was reduced upon guadipyr exposure. Simultaneously, the suppression of steroid hormone 20-hydroxyecdysone receptor and response genes, such as BR-C Z4, was detected in the exposed groups. The decreased expression of these immune regulatory pathwayrelated and 20-hydroxyecdysone signal pathway-related genes indicated that the immune system of silkworms was affected by low-dose guadipyr. Our results revealed the negative effects of guadipyr on silkworms and highlighted the unneglectable toxicity of low-dose guadipyr to this economic insect. Given the risk, it is necessary to control the application of guadipyr in or around the mulberry fields.
- 相关文献
作者其他论文 更多>>
-
Rice false smut pathogen: implications for mycotoxin contamination, current status, and future perspectives
作者：Zhou, Lei;Zheng, Hongxia;Zhang, Zhenhao;Wen, Junli;Sajid, Ashara;Chen, Liezhong;Mubeen, Mustansar;Iftikhar, Yasir;Khan, Raja Asad Ali;Solanki, Manoj Kumar;Solanki, Manoj Kumar;Sohail, Muhammad Aamir;Kumar, Ajay;El Sayed Massoud, Ehab
关键词：rice; smut; RFS; mycotoxin; infection process
-
A systemic study of cyenopyrafen in strawberry cultivation system: Efficacy, residue behavior, and impact on honeybees (Apis mellifera L.)
作者：Ye, Hui;Jiang, Jinhua;Lei, Yuan;Fang, Nan;Luo, Yuqin;Li, Yanjie;Wang, Xiangyun;He, Hongmei;Yu, Jianzhong;Xu, Zhenlan;Zhang, Changpeng;Cheng, Youpu;Li, Yanjie;Zhang, Changpeng
关键词：Strawberry; Cyenopyrafen; Residue; Honeybee; Gut microbiota; RNA-Seq
-
Glycometabolic disorder induced by chronic exposure to low-concentration imidacloprid in zebrafish
作者：Hou, Jiayin;Zhang, Lulu;Xu, Wanghui;Liu, Zhiyu;Yu, Jianzhong;Yu, Ruixian;Chen, Liezhong;Zhang, Lulu;Liu, Zhiyu;Xu, Wanghui
关键词：Imidacloprid; Zebrafish; Glucose homeostasis; Intestinal flora; Ecological risk
-
Tuning the Dynamic Reaction Balance of CRISPR/Cas12a and RPA in One Pot: A Key to Switch Nucleic Acid Quantification
作者：Yao, Zhihao;Wu, Qun;Yao, Zhihao;Xu, Yan;Wu, Qun;Yao, Zhihao;Xu, Yan;Wu, Qun;Yao, Zhihao;He, Kaiyu;Wang, Hongmei;Wang, Qiang;Xu, Xiahong;Wang, Liu;Yao, Zhihao;He, Kaiyu;Wang, Hongmei;Wang, Qiang;Xu, Xiahong;Wang, Liu;Feng, Suyin;Ding, Xiaoqing;Wang, Liu
关键词：quantification; CRISPR/Cas12a; isothermal amplification; nucleic acid; one pot
-
Carbendazim residue in plant-based foods in China: Consecutive surveys from 2011 to 2020
作者：Wang, Dou;Yang, Guiling;Luo, Ting;Guo, Hao;Pan, Liying;Wang, Yanhua;Wang, Qiang;Yun, Xiao;Du, Wei;Wang, Pu;Zhang, Qinghua;Li, Yun;Lin, Nan;Li, Yun
关键词：Carbendazim; Plant-based foods; China; Spatial-temporal variations; Exposure and risk assessment
-
Current-use pesticides monitoring and ecological risk assessment in vegetable soils at the provincial scale
作者：Zuo, Wei;Zhao, Yang;Qi, Peipei;Zhang, Chunrong;Zhao, Xueping;Wu, Shenggan;An, Xuehua;Liu, Xinju;Cheng, Xi;Tang, Tao;Yu, Yijun
关键词：Soil; Pesticide residue; Spatial distribution; Vegetable type; Ecological risk assessment
-
Long-term biogas slurry application increases microbial necromass but not plant lignin contribution to soil organic carbon in paddy soils as regulated by fungal community
作者：Chen, Zhaoming;Ma, Jinchuan;Ma, Junwei;Ye, Jing;Yu, Qiaogang;Zou, Ping;Sun, Wanchun;Lin, Hui;Wang, Feng;Wang, Qiang;Zhao, Xinlin
关键词：Soil organic carbon; Lignin phenols; Microbial necromass; Microbial community structure; Biogas slurry
