Perfluorocarboxylic Anhydrides Triggered Cyclization: Access to 4-Perfluoroalkylpyridines
文献类型： 外文期刊
作者： Wang, Zeng 1 ; You, Chenhui 1 ; Wang, Changfang 3 ; Weng, Zhiqiang 1 ;
作者机构： 1.Fuzhou Univ, Coll Chem, State Key Lab Photocatalysis Energy & Environm, Fuzhou 350108, Fujian, Peoples R China
2.Fuzhou Univ, Coll Chem, Key Lab Mol Synth & Funct Discovery, Fuzhou 350108, Fujian, Peoples R China
3.Fujian Acad Agr Sci, Inst Plant Protect, Fuzhou 350013, Fujian, Peoples R China
期刊名称：JOURNAL OF ORGANIC CHEMISTRY （ 影响因子：4.354； 五年影响因子：4.082 ）
ISSN： 0022-3263
年卷期： 2019 年 84 卷 22 期
页码：
收录情况： SCI
摘要： A double nucleophilic addition-cyclization-elimination cascade is developed, that allows various 2,6-diaryl-4-perfluoroalkylpyridines to be synthesized in one step from easily available enamides and perfluorocarboxylic anhydrides. The procedure is also operationally simple and scalable and provides access to the facial construction of 4-fluoroalkylpyridines, which are of great interest in medicinal chemistry.
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