文献类型： 外文期刊

作者： Ji, F. J. ¹ ; Wang, L. X. ¹ ; Yang, H. S. ¹ ; Hu, A. ¹ ; Yin, Y. L. ¹ ;

作者机构： 1.Hunan Normal Univ, Hunan Int Joint Lab Anim Intestinal Ecol & Hlth, Lab Anim Nutr & Human Hlth, Coll Life Sci, 36 Lushan Rd, Changsha 410081, Peoples R China

2.Chinese Acad Trop Agr Sci, Trop Crops Genet Resources Inst, 4 West Xueyuan Rd, Haikou 571101, Hainan, Peoples R China

3.Chinese Acad Sci, Inst Subtrop Agr, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, 644 Yuanda 2nd Rd, Changsha 410125, Peoples R China

4.Chinese Acad Sci, Inst Subtrop Agr, Natl Engn Lab Pollut Control & Waste Utilizat Liv, 644 Yuanda 2nd Rd, Changsha 410125, Peoples R China

5.Changsha Med Univ, Academician Workstn, 1501 Leifeng Rd, Changsha 410219, Peoples R China

关键词： swine; weaning stress; functional amino acid; barrier function; epithelial cell renewal

期刊名称：ANIMAL （ 影响因子：3.24； 五年影响因子：3.223 ）

ISSN： 1751-7311

年卷期： 2019 年 13 卷 11 期

页码：

收录情况： SCI

摘要： The gut is composed of a single layer of intestinal epithelial cells and plays important roles in the digestion and absorption of nutrients, immune and barrier functions and amino acid metabolism. Weaning stress impairs piglet intestinal epithelium structural and functional integrities, which results in reduced feed intake, growth rates and increased morbidity and mortality. Several measures are needed to maintain swine gut development and growth performance after weaning stress. A large body of evidence indicates that, in weaning piglets, glutamine, a functional amino acid, may improve growth performance and intestinal morphology, reduce oxidative damage, stimulate enterocyte proliferation, modulate cell survival and death and enhance intestinal paracellular permeability. This review focuses on the effects of glutamine on intestinal health in piglets. The aim is to provide evidentiary support for using glutamine as a feed additive to alleviate weaning stress.