Effects of Environmental Hypoxia on Serum Hematological and Biochemical Parameters, Hypoxia-Inducible Factor (hif) Gene Expression and HIF Pathway in Hybrid Sturgeon (Acipenser schrenckii ♂ x Acipenser baerii ♀)
文献类型： 外文期刊
作者： Ren, Yuanyuan 1 ; Tian, Yuan 2 ; Cheng, Bo 1 ; Liu, Yang 3 ; Yu, Huanhuan 4 ;
作者机构： 1.Chinese Acad Fishery Sci, Key Lab Control Qual & Safety Aquat Prod, Minist Agr & Rural Affairs, Beijing 100141, Peoples R China
2.Ocean Univ China, Key Lab Mariculture, Minist Educ, Qingdao 266003, Peoples R China
3.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, State Key Lab Mariculture Biobreeding & Sustainabl, Qingdao 266071, Peoples R China
4.Beijing Acad Agr & Forestry Sci, Fisheries Sci Inst, Beijing 100068, Peoples R China
关键词： hypoxia; physiological response; hypoxia-induced factor; HIF pathway; hybrid sturgeon
期刊名称：GENES （ 影响因子：2.8； 五年影响因子：3.3 ）
ISSN：
年卷期： 2024 年 15 卷 6 期
页码：
收录情况： SCI
摘要： Hypoxia is a globally pressing environmental problem in aquatic ecosystems. In the present study, a comprehensive analysis was performed to evaluate the effects of hypoxia on physiological responses (hematology, cortisol, biochemistry, hif gene expression and the HIF pathway) of hybrid sturgeons (Acipenser schrenckii male x Acipenser baerii female). A total of 180 hybrid sturgeon adults were exposed to dissolved oxygen (DO) levels of 7.00 +/- 0.2 mg/L (control, N), 3.5 +/- 0.2 mg/L (moderate hypoxia, MH) or 1.00 +/- 0.1 mg/L (severe hypoxia, SH) and were sampled at 1 h, 6 h and 24 h after hypoxia. The results showed that the red blood cell (RBC) counts and the hemoglobin (HGB) concentration were significantly increased 6 h and 24 h after hypoxia in the SH group. The serum cortisol concentrations gradually increased with the decrease in the DO levels. Moreover, several serum biochemical parameters (AST, AKP, HBDB, LDH, GLU, TP and T-Bil) were significantly altered at 24 h in the SH group. The HIFs are transcription activators that function as master regulators in hypoxia. In this study, a complete set of six hif genes were identified and characterized in hybrid sturgeon for the first time. After hypoxia, five out of six sturgeon hif genes were significantly differentially expressed in gills, especially hif-1 alpha and hif-3 alpha, with more than 20-fold changes, suggesting their important roles in adaptation to hypoxia in hybrid sturgeon. A meta-analysis indicated that the HIF pathway, a major pathway for adaptation to hypoxic environments, was activated in the liver of the hybrid sturgeon 24 h after the hypoxia challenge. Our study demonstrated that hypoxia, particularly severe hypoxia (1.00 +/- 0.1 mg/L), could cause considerable stress for the hybrid sturgeon. These results shed light on their adaptive mechanisms and potential biomarkers for hypoxia tolerance, aiding in aquaculture and conservation efforts.
- 相关文献
作者其他论文 更多>>
-
Enhancing potato leaf protein content, carbon-based constituents, and leaf area index monitoring using radiative transfer model and deep learning
作者：Feng, Haikuan;Fan, Yiguang;Ma, Yanpeng;Liu, Yang;Chen, Riqiang;Bian, Mingbo;Fan, Jiejie;Yang, Guijun;Zhao, Chunjiang;Feng, Haikuan;Zhao, Chunjiang;Yue, Jibo;Fu, Yuanyuan;Leng, Mengdie;Jin, Xiuliang;Zhao, Yu
关键词：Potato; Deep learning; Radiative transfer model; Transfer learning; Leaf protein content
-
Segmentation and Fractional Coverage Estimation of Soil, Illuminated Vegetation, and Shaded Vegetation in Corn Canopy Images Using CCSNet and UAV Remote Sensing
作者：Zhang, Shanxin;Yue, Jibo;Shu, Meiyan;Zhang, Shanxin;Wang, Xiaoyan;Feng, Haikuan;Feng, Haikuan;Liu, Yang
关键词：segmentation; digital camera; corn; deep learning
-
Impact of Faba Bean (Vicia faba L.) Diet and Subsequent Withdrawal on GIFT Tilapia (Oreochromis niloticus) Muscle Quality
作者：Xu, Guanling;Xing, Wei;Li, Tieliang;Zhang, Ying;Song, Tingting;Yu, Huanhuan;Luo, Lin;Wei, Shibo
关键词：tilapia (GIFT;
Oreochromis niloticus ); textural quality; faba beans (Vicia faba L.); immunity; antioxidant activity -
Estimation of potato above-ground biomass based on the VGC-AGB model and deep learning
作者：Feng, Haikuan;Fan, Yiguang;Bian, Mingbo;Liu, Yang;Chen, Riqiang;Ma, Yanpeng;Fan, Jiejie;Yang, Guijun;Zhao, Chunjiang;Yue, Jibo;Feng, Haikuan;Zhao, Chunjiang
关键词：Hyperspectral; Above-ground biomass; Potato; Deep learning; Leaf area index
-
Distribution and bioaccumulation of prometryn in simulated aquatic ecosystems
作者：Peng, Jiaqi;Fan, Ruiqi;Ren, Yuanyuan;Yang, Yan;Mu, Yingchun;Cheng, Bo;Peng, Jiaqi;Fan, Ruiqi;Ren, Yuanyuan;Yang, Yan;Mu, Yingchun;Cheng, Bo;Peng, Jiaqi;Fan, Ruiqi;Ren, Yuanyuan;Yang, Yan;Mu, Yingchun;Cheng, Bo;Zhang, Xin;Wang, Saisai
关键词：prometryn; tilapia (
Oreochromis niloticus ); Asian clam (Corbicula fluminea ); simulated aquatic ecosystems; distribution; bioaccumulation -
Utilizing UAV-based hyperspectral remote sensing combined with various agronomic traits to monitor potato growth and estimate yield
作者：Liu, Yang;Feng, Haikuan;Fan, Yiguang;Fan, Jiejie;Ma, Yanpeng;Chen, Riqiang;Bian, Mingbo;Yang, Guijun;Liu, Yang;Yue, Jibo;Yang, Fuqin
关键词：Crop growth monitoring; Potato yield; Crop traits; UAV; Hyperspectral
-
Withdrawal Time Estimation and Dietary Risk Assessment of Sulfamethoxazole in GIFT Tilapia (GIFT Oreochromis niloticus) After Oral Administration
作者：Wang, Xinyue;Xia, Sudong;Wang, Xiaoyu;Wang, Xinyue;Fan, Ruiqi;Ren, Yuanyuan;Mu, Yingchun;Cheng, Bo;Wang, Saisai;Zhang, Xin
关键词：sulfamethoxazole; residue; elimination; withdrawal period; antibiotics; health risk
