Fabrication, characterization, and bioactivity of self-assembled carrier-free colloidal dispersions from Citrus x Limon 'Rosso' essential oil and tea polyphenols
文献类型： 外文期刊
作者： Cheng, Fangying 1 ; Chen, Mianhong 1 ; Duan, Zhihao 1 ; Zou, Ying 1 ; He, Yunxia 1 ; Zeng, Fanke 1 ; Yuan, Yuan 1 ; Fu, Tiaokun 1 ; Tu, Hao 1 ; Li, Ruyi 1 ; Li, Jihua 1 ; Zhou, Wei 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Agr Prod Proc Res Inst, Key Lab Trop Crop Prod Proc Minist Agr & Rural Aff, Zhanjiang 524001, Guangdong, Peoples R China
2.Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Hubei, Peoples R China
3.Yunnan Agr Univ, Coll Food Sci & Technol, Kunming 650000, Peoples R China
关键词： Tea polyphenols; Colloids; Self-assembly; Carrier-free nanodelivery system; Citrus x Limon 'Rosso' essential oil
期刊名称：FOOD CHEMISTRY （ 影响因子：9.8； 五年影响因子：9.7 ）
ISSN： 0308-8146
年卷期： 2024 年 457 卷
页码：
收录情况： SCI
摘要： Carrier-free nanodelivery systems are fully self-assembled from active ingredients through interactions, offering the advantages of green, safe, and large-scale manufacturing. To improve the dispersion of Citrus x limon 'Rosso' peel essential oil (CEO) in water and boost the biological activity of CEO and tea polyphenols (TP), selfassembled CEO-TP colloidal dispersions (CEO-TP Colloids) were fabricated through sonication without surfactants or carriers. The optimal CEO and TP concentrations in the CEO-TP Colloids were determined to be 10.0 and 20.0 mg/mL by particle size and stability analyzer, respectively. The CEO self-assembled with TP to form spherical nanoparticles through hydrophobic and hydrogen-bonding interactions, whereas the CEO in CEO-TP Colloids weakened TP intramolecular aggregation. Meanwhile, the CEO-TP Colloids showed synergistic effects with better antibacterial, cellular antioxidant, and anti-inflammatory activities than single components. This study opens up the possibility of carrier-free co-delivery of hydrophobic and hydrophilic active components developed into food-grade formulations with multiple bioactivities.
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